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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Comparison between emerging Q fever in French Guiana and endemic Q fever in Marseille, France
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Comparison between emerging Q fever in French Guiana and endemic Q fever in Marseille, France

机译：法属圭亚那正在出现的Q热与法国马赛地方性Q热之间的比较

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摘要

Q fever is an emergent disease in French Guiana. We compared the incidence clinical and serologic profiles between patients from Cayenne, French Guiana and Marseille inmetropolitan France during a four-year period. The annual incidence of diagnosed acute Q fever was significantly higher in Cayenne (17.5/100,000) than in Marseille (1.9/100,000) (P = 0.0004), but not the annual incidence of endocarditis (1.29 versus 0.34/100,000). Most patients had fever (97%) and pneumonia (83%) in Cayenne versus 81% and 8% in Marseille (P < 0.0001 and P < 0.0001, respectively) but transaminitis was more common in patients from Marseille (54% versus 32%; P < 0.0001). The proportion of patients with cardiovascular infections was significantly lower in Cayenne (7%) than in Marseille (17%) ( P = 0.017), although they showed a stronger immune response with higher levels of phase I IgG (P = 0.024). The differing epidemiology, clinical, and serologic responses of patients from Cayenne and Marseille suggest a different source of infection and a different strain of Coxiella burnetii.
机译：Q热是法属圭亚那的一种紧急疾病。我们比较了卡宴，法属圭亚那和法国马赛都会大区患者在四年期间的临床和血清学特征。卡宴（17.5 / 100,000）的诊断为急性Q发热的年发病率显着高于马赛（1.9 / 100,000）（P = 0.0004），但心内膜炎的年发病率则没有（1.29对0.34 / 100,000）。卡宴的大多数患者发烧（97％）和肺炎（83％），而马赛则分别为81％和8％（分别为P <0.0001和P <0.0001），但马赛患者的转氨性炎更为常见（54％比32％ ; P <0.0001）。卡宴（7％）的心血管感染患者比例明显低于马赛（17％）（P = 0.017），尽管他们在I期IgG水平较高时表现出更强的免疫反应（P = 0.024）。卡宴和马赛患者的流行病学，临床和血清学反应有所不同，这表明感染源和伯氏柯氏杆菌属不同。

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