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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Permethrin-treated bed nets in the prevention of malaria and anemia in adolescent schoolgirls in western Kenya.
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Permethrin-treated bed nets in the prevention of malaria and anemia in adolescent schoolgirls in western Kenya.

机译:苄氯菊酯处理过的蚊帐可预防肯尼亚西部青少年女童的疟疾和贫血。

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The impact of insecticide (permethrin)-treated bed nets (ITNs) on the health of adolescent schoolgirls was investigated during a community-based, randomized, controlled trial of ITNs in western Kenya. Two school-based cross-sectional surveys were conducted to determine the prevalence of malaria and anemia in 644 schoolgirls 12-18 years old in a rural area with intense perennial malaria transmission. In 12- and 13-year-old schoolgirls, ITNs were associated with a reduced prevalence of all cause anemia (hemoglobin level <12 g/dL, 16.9% versus 31.4%, adjusted odds ratio [OR] = 0.38, 95% confidence interval [CI] = 0.21, 0.69%) and a 0.34 g/dL (95% CI = 0.02, 0.66) increase in mean hemoglobin concentrations. No beneficial effect on all-cause anemia (adjusted OR = 0.79, 95% CI = 0.43, 1.45) or hemoglobin concentrations (difference in mean = 0.14 g/dL, 95% CI = -0.24, 0.53) was evident in older girls. In all age groups, no effect was found on malaria parasite prevalence or density, clinical malaria, all-causemorbidity, standard measures of nutritional status and growth, or the use of antimalarials and other medications. ITNs approximately halved the prevalence of mild anemia in young, school-attending, non-pregnant, adolescent girls, but had no impact in older girls or on other malaria-associated morbidity or nutritional status.
机译:在肯尼亚西部一项基于社区的,随机,对照的ITNs试验中,研究了使用杀虫剂(苄氯菊酯)处理的蚊帐(ITNs)对青春期女学生健康的影响。进行了两项基于学校的横断面调查,以确定在常年疟疾大量传播的农村地区的644名12-18岁女学生的疟疾和贫血患病率。在12岁和13岁的女学生中,ITN与所有原因贫血的患病率降低相关(血红蛋白水平<12 g / dL,分别为16.9%和31.4%,校正后的优势比[OR] = 0.38,置信区间为95% [CI] = 0.21,0.69%)和平均血红蛋白浓度增加0.34 g / dL(95%CI = 0.02,0.66)。在老年女孩中,没有发现对全因性贫血(校正后的OR = 0.79,95%CI = 0.43,1.45)或血红蛋白浓度(平均值差异= 0.14 g / dL,95%CI = -0.24,0.53)没有有益作用。在所有年龄组中,未发现对疟疾寄生虫的流行或密度,临床疟疾,所有原因的发病率,营养状况和生长的标准措施或抗疟药和其他药物的使用没有影响。 ITN使上学,未怀孕,未怀孕的年轻女孩的轻度贫血的患病率大约降低了一半,但对年长的女孩或其他与疟疾相关的发病率或营养状况没有影响。

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