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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Serology and eosinophil count in the diagnosis and management of strongyloidiasis in a non-endemic area.
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Serology and eosinophil count in the diagnosis and management of strongyloidiasis in a non-endemic area.

机译：血清学检查和嗜酸性粒细胞计数在非流行地区诊断和治疗强弓形虫病。

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摘要

Strongyloidiasis is a chronic infection that may result in significant morbidity; however, diagnosis and management remain problematic. The objective of this study was to 1) evaluate the demographic, clinical, and laboratory features of 76 consecutive individuals who had Strongyloides stercoralis larvae identified in their fecal specimens; 2) determine the sensitivity of the Centers for Disease Control and Prevention (CDC) enzyme immunoassay (EIA) for detecting antibodies to Strongyloides in those with confirmed infection; and 3) assess the serologic responses and changes in eosinophil counts following treatment. Most (96%) cases occurred in immigrants, but some patients had immigrated as long as 40 years earlier. The CDC Strongyloides EIA had a sensitivity of 94.6% (95% confidence interval = 92.0-97.2%) in this patient population with proven infection. Serologic and eosinophil counts decreased after therapy, suggesting that they may be useful markers of treatment success.
机译：圆线虫病是一种慢性感染，可能导致重大发病。但是，诊断和管理仍然存在问题。这项研究的目的是：1）评估粪便标本中鉴定出的76名连续性硬皮蝇幼虫的连续人群的人口统计学，临床和实验室特征; 2）确定疾病控制和预防中心（CDC）酶免疫测定（EIA）在已确诊感染者中检测抗线虫抗体的敏感性; 3）评估治疗后的血清学反应和嗜酸性粒细胞计数的变化。大多数病例（96％）发生在移民中，但有些患者早在40年前就已移民。在已证明感染的该患者人群中，CDC圆线虫EIA的敏感性为94.6％（95％置信区间= 92.0-97.2％）。治疗后血清学和嗜酸性粒细胞计数降低，表明它们可能是治疗成功的有用标志。

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