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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Hepatosplenic morbidity in schistosomiasis japonica: evaluation with Doppler sonography.
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Hepatosplenic morbidity in schistosomiasis japonica: evaluation with Doppler sonography.

机译：日本血吸虫病的肝脾发病：用多普勒超声检查评估。

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摘要

In Southeast Asia, schistosomiasis japonica is an important cause of hepatic fibrosis and gastrointestinal hemorrhage. Reliable methods to investigate portal hypertension (PHT) clinically and epidemiologically on community level are lacking. Doppler sonography is an established tool for investigating PHT in hospital settings. In Leyte, The Philippines, 137 individuals underwent color Doppler sonography, stool examination, and serology for hepatitis B and C, liver cell injury and cholestasis. A total of 85% of the study population had been infected with Schistosoma japonicum. Sonographically, periportal liver fibrosis was seen in 25% and reticular echogenicities (network pattern) in 44%. Portal blood flow was decreased or portosystemic collaterals were present in 10% (adults throughout) and correlated with periportal fibrosis, but not with network lesions. Chronic viral hepatitis was rare. Thus, hepatic lesions are frequent in adults but not in children in areas endemic for S. japonicum. Periportal liver fibrosis indicates a risk of PHT, and network pattern fibrosis apparently does not. Doppler sonography is suitable for research under tropical field conditions.
机译：在东南亚，日本血吸虫病是肝纤维化和胃肠道出血的重要原因。缺乏在社区一级进行临床和流行病学调查的可靠方法。多普勒超声检查是在医院环境中调查PHT的既定工具。在菲律宾的莱特（Leyte），有137人接受了彩色多普勒超声检查，粪便检查以及针对乙肝和丙肝，肝细胞损伤和胆汁淤积的血清学检查。共有85％的研究人群感染了日本血吸虫。超声检查发现门静脉周围肝纤维化占25％，网状回声（网络模式）占44％。门脉血流减少或门静脉侧支的比例为10％（成年成人），与门静脉周围纤维化相关，但与网络病变无关。慢性病毒性肝炎很少见。因此，在日本血吸虫流行地区，肝损伤在成人中很常见，而在儿童中则不常见。周围肝纤维化表明存在PHT风险，而网络型纤维化显然没有。多普勒超声检查适合在热带野外条件下进行研究。

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