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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Reduction in infection with Plasmodium falciparum one year after the introduction of malaria control interventions on Bioko Island, Equatorial Guinea.
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Reduction in infection with Plasmodium falciparum one year after the introduction of malaria control interventions on Bioko Island, Equatorial Guinea.

机译：在赤道几内亚比奥科岛实施疟疾控制干预措施一年后，减少了恶性疟原虫的感染。

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摘要

The Bioko Island Malaria Control Project was initiated in 2003 to substantially reduce malaria on the island of Bioko in Equatorial Guinea. The intervention consisted of generalized indoor residual spraying during the first year of the project. Case management and related measures were introduced during the second year. Two large household and parasitemia surveys of children 2 to < 15 years of age were carried out in 2004 and 2005, respectively, to assess the effect of the intervention after the first year. Patient records were collected retrospectively from one district hospital and analyzed for a comparison of pre-intervention and post-intervention periods. Overall mean prevalence of P. falciparum infection reduced from 46% (95% confidence interval [CI] = 40-51%) at baseline in 2004 to 31% (95% CI = 24-40%) in 2005 (P < 0.001). When the 12-month pre-intervention period was compared with the 12-month post-intervention period, there was a modest but statistically significant reduction in the number of malaria cases among hospital patients.
机译：Bioko岛疟疾控制项目于2003年启动，旨在大幅度减少赤道几内亚Bioko岛上的疟疾。干预措施包括在项目的第一年进行全面的室内残留喷涂。第二年引入了案件管理和相关措施。 2004年和2005年分别对2至15岁以下的儿童进行了两次大型家庭和寄生虫病调查，以评估第一年后干预措施的效果。回顾性地从一家地区医院收集患者记录，并进行分析以比较干预前和干预后的时间。恶性疟原虫感染的总体平均患病率从基线时的46％（95％置信区间[CI] = 40-51％）在2004年降低到2005年的31％（95％CI = 24-40％）（P <0.001） 。将干预前的12个月与干预后的12个月进行比较，医院患者中疟疾病例的数量有所减少，但在统计学上具有显着统计学意义。

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