首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Catacamas virus, a hantaviral species naturally associated with Oryzomys couesi (Coues' oryzomys) in Honduras.
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Catacamas virus, a hantaviral species naturally associated with Oryzomys couesi (Coues' oryzomys) in Honduras.

机译:卡塔卡马斯病毒,一种与洪都拉斯的Oryzomys couesi(Coues'y oryzomys)自然相关的汉塔病毒。

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摘要

The primary objective of this study was to extend our knowledge of the geographical distribution, genetic diversity, and natural host associations of the hantaviruses indigenous to North America. Antibody to a hantavirus was found in 5 (20.8%) of 24 Coues' oryzomys (Oryzomys couesi) and none of 41 other rodents captured near the town of Catacamas in eastern Honduras, and a hantavirus was isolated from one of the antibody-positive Coues' oryzomys. Analyses of nucleotide and amino acid sequence data indicated that the viral isolate is a strain of a novel hantaviral species (proposed species name "Catacamas virus") that is phylogenetically most closely related to Bayou virus, a hantaviral species that is principally associated with Oryzomys palustris (marsh oryzomys) in the southeastern United States. Catacamas virus is the first evidence for the occurrence of a hantaviral species in Honduras and the first evidence that a hantaviral species is naturally associated with an Oryzomys species other than O. palustris.
机译:这项研究的主要目的是扩展我们对北美土著汉坦病毒的地理分布,遗传多样性和自然寄主协会的了解。在洪都拉斯东部卡塔卡马斯镇附近捕获的24例Coues'oryzomys(Oryzomys couesi)中有5株(20.8%)发现了汉坦病毒的抗体,而在洪都拉斯东部卡塔卡马斯镇附近未捕获到其他41只啮齿动物,并且从其中一种抗体阳性的Coues中分离出了汉坦病毒Oryzomys。核苷酸和氨基酸序列数据的分析表明,该病毒分离株是一种新型汉坦病毒物种(拟种名称为“卡塔卡马斯病毒”)的菌株,在系统发育上与巴尤病毒密切相关,后者是一种主要与谷Or相关的汉霍病毒物种。 (沼泽oryzomys)在美国东南部。卡塔卡马斯病毒是洪都拉斯出现汉塔维拉物种的第一个证据,也是汉塔维拉物种与除鼠尾草以外的其他Oryzomys物种自然相关的第一个证据。

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