• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Experimentally infected human body lice (pediculus humanus humanus) as vectors of Rickettsia rickettsii and Rickettsia conorii in a rabbit model.
【24h】

Experimentally infected human body lice (pediculus humanus humanus) as vectors of Rickettsia rickettsii and Rickettsia conorii in a rabbit model.

机译：实验感染的人体虱子（pediculus humanus humanus）是立克次体立克次体和锥状立克次体在兔模型中的载体。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The human body louse, the natural vector of Rickettsia prowazekii, is able to experimentally transmit the normally flea-borne rickettsia R. typhi, suggesting that the relationships between the body louse and rickettsiae are not specific. We used our experimental infection model to test the ability of body lice to transmit two prevalent tick-borne rickettsiae. Each of two rabbits was made bacteremic by injecting intravenously 2 x 10(6) plaque-forming units of either R. rickettsii or R. conorii. Four hundred body lice were infected by feeding on the bacteremic rabbit and were compared with 400 uninfected lice. Each louse group was fed once a day on a separate seronegative rabbit. The survival of infected lice was not different from that of uninfected controls. Lice remained infected for their lifespan, excreted R. rickettsii and R. conorii in their feces, but did not transmit the infection to their progeny. The nurse rabbit of uninfected lice remained asymptomatic and seronegative. Those rabbits used to feed infected lice developed bacteremia and seroconverted. Although the body louse is not a known vector of spotted fevers, it was able in our study to acquire, maintain, and transmit both R. rickettsii and R. conorii.
机译：人体虱子是立克次体立克次体的天然载体，能够通过实验传播正常的蚤类立克次体伤寒立克次体，这表明人体虱子与立克次体之间的关系不是特异性的。我们使用实验感染模型来测试体虱传播两种流行的tick传立克次体的能力。通过静脉内注射R.rickettsii或R. conorii的2 x 10（6）噬菌斑形成单位，将两只兔子中的每只制成细菌。取食该菌兔感染了400只虱子，并与400只未感染的虱子进行了比较。每个虱子组每天在单独的血清阴性兔子上喂养一次。被感染的虱子的存活与未感染的对照组没有不同。虱子一生都受到感染，排泄物中的R. rickettsii和R. conorii排泄，但没有将感染传播给子代。未感染虱子的哺乳兔仍无症状和血清阴性。那些用来喂养感染的虱子的兔子发展成菌血症并发生血清转化。尽管体虱不是斑疹热的已知媒介，但在我们的研究中，它能够捕获，维持和传播立克次氏菌和康乃尔氏菌。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号