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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >High Prevalence of Mansonella perstans Filariasis in Rural Senegal
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High Prevalence of Mansonella perstans Filariasis in Rural Senegal

机译:塞内加尔农村的曼森氏菌丝虫病高发

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摘要

Large parts of African and American countries are colonized by Mansonella, a very common but poorly described filarial nematode. Bloodsucking flies of the genus Culicoides are suspected to be the vector of Mansonella perstans, but no study in Senegal has confirmed that Culicoides can transmit the parasite. Designed specific real-time quantitative polymerase chain reaction (qPCR) can be used to identify microfilaria in stained blood smears. This study was performed in July and December 2010 in the southeastern Senegal, which is known to be endemic for M. perstans. We analyzed 297 blood smears from febrile and afebrile resident people by qPCR. The global prevalence of M. perstans was approximately 14.5% in both febrile and afebrile individuals. The age group of > 30 years had the highest prevalence (22.0%). No Culicoides among 1,159 studied specimens was positive for M. perstans and its vector in Senegal still requires identification.
机译:非洲裔美国国家的大部分地区都被曼森氏菌(Mansonella)所定殖,曼森氏菌是一种非常常见但鲜为人知的丝状线虫。 Culicoides属的吸血蝇被怀疑是波斯曼氏菌的媒介,但塞内加尔尚无研究证实Culicoides可传播寄生虫。设计的特定实时定量聚合酶链反应(qPCR)可用于鉴定血涂片中的微丝虫病。这项研究于2010年7月和2010年12月在塞内加尔东南部进行,该地区被认为是波斯毛支气管炎的地方病。我们通过qPCR分析了297例来自高热和低热居民的血液涂片。高热和低热个体中,毛状支原体的全球患病率约为14.5%。年龄大于30岁的年龄段患病率最高(22.0%)。在1,159个被研究的标本中,没有Culicoides呈阳性表达。

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