...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >High prevalence of asymptomatic Plasmodium vivax and Plasmodium falciparum infections in native Amazonian populations.
【24h】

High prevalence of asymptomatic Plasmodium vivax and Plasmodium falciparum infections in native Amazonian populations.

机译：无症状的间日疟原虫和恶性疟原虫感染在当地亚马逊人群中普遍存在。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The epidemiology of malaria in 2 riverine localities in Rondjnia, Brazilian western Amazjnia, was assessed by a 1-year study at Portuchuelo, and a cross-sectional survey at riverine communities at Rio Machado (= Ji-Parana). Plasmodium spp. infections were diagnosed by light microscopy and by polymerase chain reaction (PCR) amplification of ribosomal DNA. PCR was 6-7 times more efficient than microscopy for detecting plasmodial infections. Both Plasmodium vivax and Plasmodium falciparum infections occurred as asymptomatic and symptomatic forms of the disease. The relation between symptomatic and asymptomatic clinical forms was roughly similar for both species of Plasmodium. Symptomless patients were monitored for 2 months. The prevalence of symptomless infections was 4-5 times higher than the symptomatic ones--respectively, 20% and 4.6% for Portuchuelo and 49.5% and 10% for Ji-Parana. Symptomatic malaria occurred mostly in patients in younger age groups. In contrast, there was a significant association of symptomless malaria with older age groups (medians of 26.5 and 21 years, respectively, for Portuchuelo and Ji-Parana), whereas the age medians for symptomatic malaria were 14 and 8 years, respectively, in the 2 regions. Symptomatic malaria also was more prevalent in groups living for shorter times in Amazjnia (13 and 4 years, respectively, for Portuchuelo and Ji-ParanA) as compared with symptomless malaria, which was more prevalent in groups living for longer periods in the region (medians of 25.5 and 18 years, respectively, for Portuchuelo and Ji-Parana). The high prevalence of symptomless malaria may pose new problems for the currently adopted strategy for the control of malaria in the Amazonian region, which is essentially based on the treatment of symptomatic patients.
机译：在Portuchuelo进行了为期1年的研究，并在Rio Machado（= Ji-Parana）对沿河社区进行了横断面调查，评估了巴西西部马其顿州Rondjnia的2个沿河地区的疟疾流行病学。疟原虫属通过光学显微镜和核糖体DNA的聚合酶链反应（PCR）扩增诊断感染。 PCR检测显微镜下疟原虫感染的效率是显微镜的6-7倍。间日疟原虫和恶性疟原虫感染均以无症状和症状形式出现。两种疟原虫的症状和无症状临床形式之间的关系大致相似。监测无症状患者2个月。无症状感染的发生率是有症状感染的4-5倍-分别是Portuchuelo的20％和4.6％，Ji-Parana的49.5％和10％。有症状的疟疾主要发生在年轻年龄段的患者中。相比之下，无症状疟疾与较高年龄组有显着关联（Portuchuelo和Ji-Parana分别为26.5和21岁），而有症状疟疾的年龄中位数分别为14岁和8岁。 2个地区。与无症状疟疾相比，在无症状疟疾中，在亚马逊地区生活时间较短的人群中更普遍（Portuchuelo和Ji-ParanA分别为13和4年），而无症状疟疾在该地区生活时间较长的人群中更为普遍分别是Portuchuelo和Ji-Parana的25.5岁和18岁）。无症状疟疾的高流行可能对当前在亚马逊地区控制疟疾的策略提出新问题，该策略主要基于对症患者的治疗。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号