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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Mefloquine use and hospitalizations among US service members, 2002-2004.
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Mefloquine use and hospitalizations among US service members, 2002-2004.

机译：2002年至2004年，美氟喹在美国服役人员中的使用和住院治疗。

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摘要

The safety of mefloquine has not been well described in military populations. This study used standard military databases for mefloquine prescriptions and hospitalizations to investigate mefloquine safety among US service members from 2002 through 2004. Mefloquine-prescribed and deployed personnel (N = 8,858) were compared with two reference groups. The reference groups comprised US service members who were not prescribed mefloquine and resided in Europe or Japan (N = 156,203) or had been otherwise deployed (N = 232,381). In comparison with active-duty US service members residing in Europe or Japan, mefloquine-prescribed service members were at statistically significant decreased hazard for any-cause hospitalization, as well as diseases of the respiratory and digestive systems, musculoskeletal system and connective tissue diseases, injuries and poisonings, ill-defined conditions, and mood disorders. These results suggest there is no association between mefloquine prescriptions and severe health effects, as measured by hospitalizations, across a wide range of outcomes.
机译：甲氟喹的安全性在军事人群中尚未得到很好的描述。这项研究使用了标准的军事数据库进行甲氟喹处方和住院治疗，以调查2002年至2004年美国服役人员中甲氟喹的安全性。将甲氟喹处方和部署人员（N = 8858）与两个参考组进行了比较。参比人群包括未服甲氟喹的美国服务人员，居住在欧洲或日本（N = 156,203）或已被调派（N = 232,381）。与居住在欧洲或日本的现役美国服务人员相比，甲氟喹处方的服务人员因任何原因住院以及呼吸系统和消化系统疾病，肌肉骨骼系统疾病和结缔组织疾病的危险性在统计学上显着降低，伤害和中毒，病情不明确以及情绪异常。这些结果表明，甲氟喹处方与在广泛结果中住院治疗所测得的严重健康影响之间没有关联。

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