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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Laboratory investigation of human deaths from vampire bat rabies in Peru.
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Laboratory investigation of human deaths from vampire bat rabies in Peru.

机译：秘鲁因吸血蝙蝠狂犬病造成的人类死亡的实验室调查。

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In the spring of 1996, multiple cases of an acute febrile illness resulting in several deaths in remote locations in Peru were reported to the Centers for Disease Control and Prevention (CDC). The clinical syndromes for these cases included dysphagia and encephalitis. Because bat bites were a common occurrence in the affected areas, the initial clinical diagnosis was rabies. However, rabies was discounted primarily because of reported patient recovery. Samples of brain tissue from two of the fatal cases were received at CDC for laboratory confirmation of the rabies diagnosis. An extensive array of tests on the formalin-fixed tissues confirmed the presence of both rabies viral antigen and nucleic acid. The virus was shown to be most closely related to a vampire bat rabies isolate. These results indicate the importance of maintaining rabies in the differential diagnosis of acute febrile encephalitis, particularly in areas where exposure to vampire bats may occur.
机译：1996年春季，疾病控制与预防中心（CDC）报告了多起急性发热性疾病病例，在秘鲁偏远地区造成多人死亡。这些病例的临床综合征包括吞咽困难和脑炎。由于蝙蝠咬伤在患病地区很普遍，因此最初的临床诊断是狂犬病。然而，狂犬病被打折的主要原因是据报道患者康复。 CDC接收了两个致命病例的脑组织样本，用于实验室确认狂犬病的诊断。在福尔马林固定的组织上进行的广泛测试证实狂犬病毒病毒抗原和核酸均存在。已显示该病毒与吸血蝙蝠狂犬病病毒分离株最密切相关。这些结果表明在狂犬性脑炎的鉴别诊断中保持狂犬病的重要性，尤其是在可能出现吸血蝙蝠的地区。

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