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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Toxoplasma gondii seropositivity and co-infection with TORCH pathogens in high-risk patients from Qatar.
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Toxoplasma gondii seropositivity and co-infection with TORCH pathogens in high-risk patients from Qatar.

机译：卡塔尔高危患者的弓形虫血清阳性和与TORCH病原体共感染。

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摘要

Testing of patients who are deemed to be at high risk for TORCH pathogens, e.g., pregnant women, their fetuses, neonates, and acquired immunodeficiency syndrome (AIDS) patients, is important so that specific treatment can be initiated. This study included 1,857 such patients between 2005 and 2008. Logistic regression was used to evaluate factors associated with Toxoplasma gondii seropositivity. Among 823 women of childbearing age, 35.1% and 5.2% tested positive for T. gondii IgG and IgM, respectively. Three infants < or = 6 months of age (0.8% of 353) were congenitally infected. Factors associated with T. gondii IgG seropositivity included older age, East Mediterranean or African nationality, positive cytomegalovirus (CMV) and herpes simplex virus (HSV)-1 serostatus, and negative rubella IgG results. The decreasing prevalence of IgM antibodies between 2005 and 2008 suggested that exposure to T. gondii from food or environmental sources declined over this period in Qatar. Population-based studies of newborns would be helpful to accurately estimate incidence of congenital toxoplasmosis.
机译：对被认为具有TORCH病原体高风险的患者（例如孕妇，其胎儿，新生儿和获得性免疫缺陷综合症（AIDS）患者）进行测试很重要，这样才能启动特异性治疗。这项研究包括2005年至2008年之间的1,857名此类患者。采用Logistic回归分析来评估与弓形虫血清反应阳性相关的因素。在823个育龄妇女中，刚地弓形虫IgG和IgM分别为35.1％和5.2％。三名<或= 6个月大的婴儿（353名的0.8％）是先天性感染的。与弓形虫IgG血清阳性相关的因素包括年龄较大，东地中海或非洲国籍，巨细胞病毒（CMV）和单纯疱疹病毒（HSV）-1血清阳性，风疹IgG阴性。 IgM抗体的流行率在2005年至2008年间下降，这表明在此期间，卡塔尔从食物或环境来源接触弓形虫的人数有所减少。基于人口的新生儿研究将有助于准确估计先天性弓形虫病的发病率。

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