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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Concurrent infections in acute febrile illness patients in Egypt.
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Concurrent infections in acute febrile illness patients in Egypt.

机译:埃及急性发热患者的同时感染。

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摘要

We report the occurrence of concurrent infections with multiple acute febrile illness (AFI) pathogens during an ongoing prospective laboratory-based surveillance in four infectious disease hospitals in urban and rural areas of Egypt from June 2005 to August 2006. Patients were screened for Leptospira, Rickettsia typhi, Brucella, or Salmonella enterica serogroup Typhi by various methods including serology, culture, and PCR. One hundred eighty-seven of 1,510 patients (12.4%) evaluated had supporting evidence for the presence of co-infections; 20 (1%) of these patients had 2 or more pathogens based upon confirmatory 4-fold rise in antibody titer, culture, and/or PCR. Most coinfected patients lived or worked in rural agricultural areas. The high coinfection rates suggest that defining the etiologies of AFI is imperative in guiding proper disease treatment, prevention, and control strategies in Egypt.
机译:我们报告了从2005年6月至2006年8月在埃及城市和农村地区的四家传染病医院正在进行的基于前瞻性实验室监测的过程中,发生了多种急性发热性病原体的并发感染。对患者进行了立克次体钩端螺旋体的筛查伤寒,布鲁氏菌或伤寒沙门氏菌血清型,可通过多种方法进行,包括血清学,培养和PCR。被评估的1,510名患者中有187名(12.4%)有支持证据表明存在合并感染。根据抗体滴度,培养物和/或PCR的确定性4倍升高,这些患者中有20(1%)有2种或更多的病原体。大多数合并感染的患者在农村农业地区生活或工作。高合并感染率表明,定义AFI的病因对指导埃及的正确疾病治疗,预防和控制策略至关重要。

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