...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Antibody response from whole-cell pertussis vaccine immunized Brazilian children against different strains of Bordetella pertussis.
【24h】

Antibody response from whole-cell pertussis vaccine immunized Brazilian children against different strains of Bordetella pertussis.

机译：来自全细胞百日咳疫苗的抗体反应使巴西儿童免疫了百日咳博德特氏菌不同菌株。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Bordetella pertussis is a gram-negative bacillus that causes the highly contagious disease known as pertussis or whooping cough. Antibody response in children may vary depending on the vaccination schedule and the product used. In this study, we have analyzed the antibody response of cellular pertussis vaccinated children against B. pertussis strains and their virulence factors, such as pertussis toxin, pertactin, and filamentous hemagglutinin. After the completion of the immunization process, according to the Brazilian vaccination program, children serum samples were collected at different periods of time, and tested for the presence of specific antibodies and antigenic cross-reactivity. Results obtained show that children immunized with three doses of the Brazilian whole-cell pertussis vaccine present high levels of serum antibodies capable of recognizing the majority of the components present in vaccinal and non-vaccinal B. pertussis strains and their virulence factors for at least 2 years after the completion of the immunization procedure.
机译：百日咳博德特氏菌是一种革兰氏阴性杆菌，可引起高度传染性疾病，称为百日咳或百日咳。儿童的抗体反应可能会根据疫苗接种时间表和使用的产品而有所不同。在这项研究中，我们分析了接种百日咳杆菌的儿童对百日咳博德特氏菌菌株及其毒力因子（如百日咳毒素，百日咳杆菌粘附素和丝状血凝素）的抗体反应。免疫程序完成后，根据巴西的疫苗接种计划，在不同时间段收集儿童血清样本，并测试特异性抗体的存在和抗原交叉反应性。获得的结果表明，用三剂巴西全细胞百日咳疫苗免疫的儿童的血清抗体水平高，能够识别出至少2种存在于疫苗和非疫苗百日咳博德特氏菌菌株中的大部分成分及其毒力因子。免疫程序完成后的十年。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号