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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Investigation of a sudden malaria outbreak in the isolated Amazonian Village of Saül, French Guiana, January-April 2009
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Investigation of a sudden malaria outbreak in the isolated Amazonian Village of Saül, French Guiana, January-April 2009

机译：2009年1月至4月，在法属圭亚那偏远的亚马逊村庄萨尔，突然发生了疟疾暴发的调查

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摘要

Malaria is endemic in French Guiana. Plasmodium falciparum and Plasmodium vivax are the predominant species responsible and Anopheles darlingi is described as the major vector. In mid-August 2008, an increase in malaria incidence was observed in Saül. A retrospective cohort survey was performed. In vitro susceptibility profiles to antimalarials were determined on P. falciparum isolates. Collections of mosquitoes were organized. The malaria attack rate reached 70.6/100. The risk of malaria increased for people between 40 and 49 years of age, living in a house not subjected to a recent indoor residual insecticide spraying or staying overnight in the surrounding forest. All isolates were susceptible. Anopheles darlingi females and larvae were collected in the village suggesting a local transmission. Our results strongly support a role of illegal mining activities in the emergence of new foci of malaria. Therefore, public health authorities should define policies to fight malaria at a transborder level.
机译：疟疾在法属圭亚那流行。恶性疟原虫和间日疟原虫是主要的病原体，而按蚊是主要的媒介。在2008年8月中旬，萨尔省的疟疾发病率有所上升。进行了回顾性队列研究。在恶性疟原虫分离株上测定了抗疟药的体外敏感性概况。组织了蚊子的收集。疟疾发作率达到70.6 / 100。对于40至49岁的人们，居住在未进行室内室内残留杀虫剂喷雾的房屋中或在周围森林中过夜的人群中，疟疾的风险会增加。所有分离株均易感。村中收集到了按蚊达令吉的雌性和幼虫，表明它们是局部传播的。我们的结果强有力地支持了非法采矿活动在新的疟疾疫源出现中的作用。因此，公共卫生当局应制定跨境抗击疟疾的政策。

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