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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Molecular epidemiology of Leptospira borgpetersenii serovar Arborea, Queensland, Australia, 1998-2005.
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Molecular epidemiology of Leptospira borgpetersenii serovar Arborea, Queensland, Australia, 1998-2005.

机译:1998年至2005年,澳大利亚昆士兰州的钩端螺旋体钩端螺旋体的分子流行病学。

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摘要

Leptospira borgpetersenii serovar Arborea is an emerging cause of leptospirosis in Australia. It was not previously recognized as an endemic serovar before the 1990s, but at that point, human infections with the serovar increased significantly. Using fluorescent-amplified fragment-length polymorphism (FAFLP) molecular typing, human and rodent isolates were compared genetically. Typing revealed 11 unique profiles among the 23 isolates examined; however, there was no clonality revealed between the human and rodent isolates. There was clonality among rodent isolates from geographically related areas. This study highlights the utility of Leptospira culture combined with FAFLP for the examination of the epidemiology of this disease.
机译:博德钩端螺旋体血清型Arborea是澳大利亚钩端螺旋体病的一个新兴原因。在1990年代之前,它以前未被认为是地方性血清型,但是那时,人类对血清型的感染显着增加。使用荧光扩增的片段长度多态性(FAFLP)分子分型,人类和啮齿动物分离株进行了遗传比较。分型显示在检查的23个分离株中有11个独特的特征。但是,在人类和啮齿动物分离株之间没有发现克隆性。来自地理相关区域的啮齿动物分离株之间具有克隆性。这项研究强调了钩端螺旋体培养与FAFLP结合用于检查这种疾病的流行病学的实用性。

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