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首页> 外文期刊>The American Journal of Forensic Medicine and Pathology: official publication of the National Association of Medical Examiners >Study of the brainstem, particularly the arcuate nucleus, in sudden infant death syndrome (SIDS) and sudden intrauterine unexplained death (SIUD).
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Study of the brainstem, particularly the arcuate nucleus, in sudden infant death syndrome (SIDS) and sudden intrauterine unexplained death (SIUD).

机译：研究婴儿猝死综合症（SIDS）和子宫内无法解释的猝死（SIUD）的脑干，特别是弓状核。

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摘要

Complete examination of the brainstem involves transverse serial 5-microm sections made throughout the entire brainstem. The number of serial sections varies from 360 in sudden intrauterine unexplained death (SIUD) to 600 in term fetuses to over 1400 sections in sudden infant death syndrome (SIDS) victims. The procedure is not applicable in all histopathological laboratories, owing to the need for additional technical personnel. The simplified procedure allows a remarkable reduction of the number of sections. The brainstem is divided into 3 blocks. The first, cranial block, extends from the border between the medulla oblongata and pons up to the upper pole of the olivary nucleus. The second, intermediate block, corresponding to the submedian area of the inferior olivary nucleus, has as reference point the obex and extends 2 to 3 mm above and below the obex itself. The third, caudal block, includes the lower pole of the inferior olivary nucleus and the lower adjacent area of the medulla oblongata. Examinations of the brainstems from 106 SIDS victims, 30 controls, and 51 stillborns underlined a remarkable variability, particularly of the arcuate nucleus. The simplified examination of the brainstem makes it possible to evaluate the structures, examining 3 specific levels, defined by morphologic reference points.
机译：对脑干的完整检查涉及整个脑干的横向连续5微米切片。连续切片的数量从子宫内无法解释的猝死（SIUD）的360个到足月胎儿的600个到婴儿猝死综合症（SIDS）受害者的1400多个不等。由于需要额外的技术人员，该程序不适用于所有组织病理学实验室。简化的程序可以显着减少段数。脑干分为3个块。第一个颅骨阻滞从延髓之间的边界延伸到脑桥直至橄榄核的上极。第二个中间块，对应于下橄榄核的中间区域，以骨灰石为参考点，并在骨灰石自身上方和下方延伸2至3毫米。第三个尾状块包括下橄榄核的下极和长延髓的下相邻区域。对106名SIDS受害者，30名对照和51名死产儿的脑干进行了检查，结果显示出了显着的变异性，尤其是弓形核的变异性。简化的脑干检查可以评估结构，检查由形态学参考点定义的3个特定水平。

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