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首页> 外文期刊>The American journal of geriatric psychiatry: official journal of the American Association for Geriatric Psychiatry >Prevalence and gender differences in late-life depression: A population-based study
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Prevalence and gender differences in late-life depression: A population-based study

机译：晚期抑郁症的患病率和性别差异：一项基于人群的研究

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Objective: The worldwide phenomenon of an aging population combined with the increasing prevalence of depression in late life are issues that need to be addressed. This study aims to estimate the frequency of depression and subthreshold depression occurring in a sample of cognitively well-functioning, community-dwelling, older Italian adults and to investigate sociodemographic and clinical correlates of depression, exploring gender differences. Methods: We used a cross-sectional analyses of survivors in a population-based study (the Faenza Project) that included 359 subjects aged 74 years and older (49.3% women). A modified version of Cambridge Examination for Mental Disorders of Elderly Persons-Revised was administered to all participants. Prevalence rates of depression and 95% confidence intervals (CIs) were estimated according to International Classification of Diseases, Tenth Revision criteria. Statistical analyses were implemented to describe sociodemographic and clinical features associated with depression. Odds ratios were estimated by multivariate logistic regression, and the dependant variable was any type of depression. Results: Overall prevalence of depression was 25.1% (95% CI: 20.6e29.6), with no evidence of gender difference. Prevalence of mild, moderate, and severe depression was 16.4% (95% CI: 12.6e20.2), 7.5% (95% CI: 4.8e10.2), and 1.1 (95% CI: e0.4e2.6), respectively. A rate of 5.6% of the population complained of subthreshold depressive symptoms. After age 81, depression occurrence decreased as age increased. The association between depression and functional measures, such as primary activity, mobility, and disability in performing household chores, were stronger in men than in women. Similarly, severely disabling conditions like stroke were more strongly associated with depression in men than in women. Conclusion: Our data suggest a disparity between men and women regarding the impact of depression on everyday life. Specific gender differences need to be taken into account for the evaluation of the depression-related burden in late life.
机译：目的：全球人口老龄化现象与晚年抑郁症患病率上升相结合是需要解决的问题。这项研究的目的是估计在认知功能良好，居住在社区的意大利老年人中，抑郁症和阈下抑郁症的发生频率，并调查抑郁症的社会人口统计学和临床​​相关性，探讨性别差异。方法：我们在一项基于人群的研究（法恩扎项目）中使用了幸存者的横断面分析，其中包括359位年龄在74岁以上的受试者（女性占49.3％）。对所有参与者进行了修订版的《剑桥老年人心理疾病考试》。根据国际疾病分类第十修订标准，估计了抑郁症的患病率和95％的置信区间（CIs）。进行统计分析以描述与抑郁症相关的社会人口统计学和临床​​特征。通过多元逻辑回归估计赔率，因变量是任何类型的抑郁。结果：总体抑郁症患病率为25.1％（95％CI：20.6e29.6），没有性别差异的证据。轻度，中度和重度抑郁症的患病率为16.4％（95％CI：12.6e20.2），7.5％（95％CI：4.8e10.2）和1.1（95％CI：e0.4e2.6），分别。有5.6％的人口抱怨阈下抑郁症状。 81岁以后，抑郁症的发生随着年龄的增长而减少。男性与女性相比，抑郁与功能性指标之间的关联性更高，例如主要活动，活动能力和家务劳动中的残疾。同样，与中风相比，中风等严重致残性疾病与男性相比，与女性抑郁症的相关性更大。结论：我们的数据表明，在抑郁症对日常生活的影响方面，男女之间存在差异。在评估晚年与抑郁相关的负担时，需要考虑特定的性别差异。

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