...
【24h】

Depression Among Older Adults After Traumatic Brain Injury: A National Analysis

机译:颅脑外伤后老年人抑郁症的国家分析

获取原文
获取原文并翻译 | 示例
           

摘要

Objective: Sequelae of traumatic brain injury (TBI) include depression, which could exacerbate the poorer cognitive and functional recovery experienced by older adults. The objective of this study was to estimate incidence rates of depression after hospital discharge for TBI among Medicare beneficiaries aged at least 65 years, quantify the increase in risk of depression after TBI, and evaluate risk factors for incident depression post-TBI. Methods: Using a retrospective analysis, the authors studied Medicare beneficiaries at least 65 years old hospitalized for TBI during 2006 to 2010 who survived to hospital discharge and had no documented diagnosis of depression before the study period (N = 67,347). Results: The annualized incidence rate of depression per 1,000 beneficiaries was 62.8 (95% confidence interval [CI]: 61.6, 64.1) pre-TBI and 123.9 (95% CI: 121.6, 126.2) post-TBI. Annualized incidence rates were highest immediately after hospital discharge and declined over the 12 months post-TBI. TBI increased the risk of incident depression in men (hazard ratio: 1.95; 95% CI: 1.84, 2.06; Wald chi(2) = 511.4, df = 1, p < 0.001) and in women (hazard ratio: 1.69; 95% CI: 1.62, 1.77; Wald chi(2) = 589.3, df = 1, p < 0.001). The strongest predictor of depression post-TBI for both men and women was discharge to a skilled nursing facility (men: odds ratio, 1.91; 95% CI, 1.77, 2.06; Wald chi(2) = 277.1, df = 1, p < 0.001; women: odds ratio, 1.72; 95% CI, 1.63, 1.83; Wald chi(2) = 324.2, df = 1, p < 0.001). Conclusion: TBI significantly increased the risk of depression among older adults, especially among men and those discharged to a skilled nursing facility. Results from this study will help increase awareness of the risk of depression post-TBI among older adults.
机译:目的:创伤性脑损伤(TBI)的后遗症包括抑郁症,这可能会加剧老年人经历的较差的认知和功能恢复。这项研究的目的是评估至少65岁的Medicare受益人TBI出院后抑郁的发生率,量化TBI后抑郁的风险增加,并评估TBI后发生抑郁的风险因素。方法:通过回顾性分析,作者研究了2006年至2010年间因TBI住院的至少65岁的Medicare受益人,他们存活至出院且在研究期之前没有记录的抑郁症诊断(N = 67,347)。结果:TBI前的年平均抑郁症发病率是每1,000名受益人62.8(95%置信区间[CI]:61.6,64.1),TBI后为123.9(95%CI:121.6,126.2)。年发病率在出院后立即最高,在TBI后的12个月中下降。 TBI增加了男性(女性的危险比:1.95; 95%CI:1.84,2.06; Wald chi(2)= 511.4,df = 1,p <0.001)和女性的女性(危险比:1.69; 95%) CI:1.62,1.77; Wald chi(2)= 589.3,df = 1,p <0.001)。男性和女性在TBI后抑郁症的最强预测指标是出院到熟练的护理机构(男性:优势比,1.91; 95%CI,1.77,2.06; Wald chi(2)= 277.1,df = 1,p < 0.001;女性:优势比为1.72; 95%CI为1.63,1.83; Wald chi(2)= 324.2,df = 1,p <0.001)。结论:TBI显着增加了老年人的抑郁风险,特别是在男性和出院后的老年人中。这项研究的结果将有助于提高老年人对TBI后抑郁症风险的认识。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号