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首页> 外文期刊>Child and adolescent psychiatric clinics of North America >Pharmacotherapy of child and adolescent depression.
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Pharmacotherapy of child and adolescent depression.

机译：儿童和青少年抑郁症的药物治疗。

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摘要

Pediatric depression is a prevalent and recurrent condition that persists into adulthood and carries significant impairment, morbidity, and risk of mortality. Although there has been a surge of pediatric antidepressant studies in recent years, depression remains largely understudied, unrecognized, and untreated in children and adolescents. Few antidepressant trials have yielded positive results in pediatric depression. Regulatory agencies recently issued warnings against the use of selective serotonin reuptake inhibitors and newer antidepressants in depressed children and adolescents because of a possible link between their use and the appearance or worsening of suicidal ideation or attempts. The authors review data on efficacy and safety of antidepressants for the treatment of pediatric depression to provide treating clinicians with a basis on which to guide their treatment recommendations.
机译：小儿抑郁症是一种普遍存在的复发性疾病，持续到成年，并伴有严重的损害，发病率和死亡风险。尽管近年来对儿童抗抑郁药的研究激增，但抑郁症仍在很大程度上被研究，未被认识和在儿童和青少年中得到治疗。很少有抗抑郁药试验在小儿抑郁症中产生阳性结果。监管机构最近发布警告，禁止在抑郁的儿童和青少年中使用选择性5-羟色胺再摄取抑制剂和新型抗抑郁药，因为它们的使用与自杀意念或尝试的出现或恶化之间可能存在联系。作者回顾了抗抑郁药治疗小儿抑郁症的有效性和安全性数据，为治疗的临床医生提供了指导其治疗建议的基础。

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