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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >Use of pro re nata medications in acute inpatient care.
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Use of pro re nata medications in acute inpatient care.

机译：在急性住院治疗中使用前列腺素药物。

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OBJECTIVES: Available evidence suggests that the use of 'as needed' (PRN; from the Latin pro re nata: for an occasion that has arisen) medications has remained a standard aspect of treatment in acute inpatient mental health units over a number of years despite lack of evidence from controlled clinical trials. The practice is one in which doctors and nurses are interdependent; that is, while doctors prescribe the medications, professional nurses are the ones who make the clinical decisions to administer them. The aim of the present study was to provide a detailed description of the circumstances surrounding the use of PRN medications across four inpatient units in Sydney. METHODS: The medical records of all patients admitted for >24h during a 2 month period were retrospectively audited for details regarding prescriptions and administrations of PRN medications. RESULTS: A total of 420 records were reviewed, producing a total of 3868 PRN medication administrations. Ninety-seven per cent of all patients were prescribed PRN medications and 93.8% were prescribed regular medications. The most frequently prescribed medications were second-generation antipsychotics for regular use along with benzodiazepine for PRN use. Nearly 84% of patients received at least one PRN medication during their admission, while patients diagnosed with personality disorder received more PRNs per day. The most common reason for PRN administration was patient agitation. The results indicated poor documentation in the prescription and documentation of PRN administrations. Also, the findings show that a small subset of the patients (5%) received >30% of all PRN medications. CONCLUSION: PRN medication use has endured as standard practice and the results of the present study are consistent with the reported frequency of use increasing slightly over the years. The combination of second-generation antipsychotics as regular medications and benzodiazepines for PRN medication is consistent with recommended treatment guidelines. The small subset of patients who were overrepresented in the PRN administrations is noteworthy.
机译：目的：现有证据表明，多年来，尽管有需要，但仍使用“按需使用”（PRN;来自拉丁语：出现的一种情况）药物已成为急性住院精神卫生部门治疗的标准方法。缺乏对照临床试验的证据。这种做法是医生和护士相互依存的一种做法。也就是说，在医生开处方的同时，由专业护士来制定临床决策来管理这些药物。本研究的目的是详细描述悉尼四个住院单元使用PRN药物的情况。方法：对2个月内入院> 24h的所有患者的病历进行回顾性审核，以了解有关PRN药物处方和给药的详细信息。结果：共审查了420条记录，共产生3868次PRN药物管理。在所有患者中，有97％的患者使用了PRN药物，有93.8％的患者使用了常规药物。处方最频繁的药物是常规使用的第二代抗精神病药以及用于PRN的苯二氮卓。入院期间将近84％的患者至少接受一种PRN药物，而诊断为人格障碍的患者每天接受更多的PRN。 PRN给药的最常见原因是患者激动。结果表明，PRN主管部门的处方和文件记录不佳。此外，研究结果表明，一小部分患者（5％）接受了所有PRN药物的> 30％。结论：PRN药物的使用已成为标准做法，并且本研究的结果与多年来报道的使用频率略有一致。作为常规药物的第二代抗精神病药与用于PRN药物的苯二氮卓类药物的组合符合推荐的治疗指南。值得注意的是，在PRN给药中代表性过多的一小部分患者。

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