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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >Prevalence and predictors of suicide attempt in an incidence cohort of 661 young people with first-episode psychosis.
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Prevalence and predictors of suicide attempt in an incidence cohort of 661 young people with first-episode psychosis.

机译：661名患有首发精神病的年轻人的发病率队列中自杀未遂的发生率和预测因素。

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OBJECTIVES: Studies investigating suicidal behaviour in psychosis rarely focus on incidence cohorts of first-episode patients. This is important, because patients who refuse study participation have higher rates of comorbid substance use disorders and longer duration of untreated psychosis as well as worse course illness, variables potentially linked to higher prevalence of suicidal behaviour. The aims of the present study were therefore to examine the prevalence and predictors of suicide and suicide attempt before and during the first 18-24 months of treatment. METHOD: A retrospective file audit of 661 patients was carried out. RESULTS: Six patients (0.9%) died by suicide, 93 (14.3%) attempted suicide prior to entry, and 57 (8.7%) did so during treatment. Predictors of suicide attempt were: previous attempt (odds ratio (OR)=45.54, 95% confidence interval (CI)=9.46-219.15), sexual abuse (OR=8.46, 95%CI=1.88-38.03), comorbid polysubstance (OR=13.63, 95%CI=2.58-71.99), greater insight (OR=0.17, 95%CI=0.06-0.49), lower baseline Global Assessment of Functioning Scale and Scale of Occupational and Functional Assessment score (OR=0.96, 95%CI=0.62-0.91; OR=0.98, 95%CI=0.95-0.99), and longer time in treatment (OR=1.05, 95%CI=1.03-1.08). CONCLUSIONS: The prevalence of suicidal behaviour was high, indicating that suicidal behaviour in incidence populations is higher than in non-epidemiological cohorts of first-episode patients. The rate of repetition of suicide attempt among the sample, however, was lower than expected, suggesting that specialist services can play a role in reducing suicide risk.
机译：目的：研究精神病患者自杀行为的研究很少集中于首发患者的发病队列。这很重要，因为拒绝参加研究的患者合并症使用率更高，未治疗的精神病持续时间更长，病程更糟，这些变量可能与自杀行为的高发有关。因此，本研究的目的是在治疗的前18-24个月之前和期间检查自杀和自杀未遂的发生率和预测因素。方法：对661例患者进行回顾性档案审核。结果：6例患者（0.9％）死于自杀，93例（14.3％）在入院前曾自杀，57例（8.7％）在治疗期间自杀。自杀未遂的预测因素是：先前的未遂尝试（比值比（OR）= 45.54，95％置信区间（CI）= 9.46-219.15），性虐待（OR = 8.46，95％CI = 1.88-38.03），共病多物质（OR = 13.63，95％CI = 2.58-71.99），洞察力更高（OR = 0.17，95％CI = 0.06-0.49），基线总体功能评估量表和职业及功能评估量表得分（OR = 0.96，95％） CI = 0.62-0.91; OR = 0.98，95％CI = 0.95-0.99），且治疗时间更长（OR = 1.05，95％CI = 1.03-1.08）。结论：自杀行为的患病率很高，表明发病率人群中的自杀行为高于首发患者的非流行病学队列。然而，样本中自杀未遂的重复率低于预期，这表明专家服务可在降低自杀风险中发挥作用。

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