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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >Internalizing versus externalizing comorbidity: neural circuit hypothesis.
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Internalizing versus externalizing comorbidity: neural circuit hypothesis.

机译：内部合并与外部合并合并症：神经回路假说。

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摘要

The aim of the present study was to review and update historical controversies in relation to the limbic system in light of advances in the neuroanatmy and neurobiology of cortico-striatal-thalamic-cortical (CSTC) neural circuits. It is hypothesized that observed comorbidities between internalizing and externalizing childhood syndromes may be better understood in terms of excess communication between subcortical brain circuits. A neuroanatomical understanding of reciprocal and non-reciprocal connections between modular circuits provides a basis for understanding previously puzzling aspects of internalizing, externalizing comorbidity. Function depends on the degree of cooperative integration of goal orientation, Pavlovian stimulus response, and operant processing in cortical-subcortical circuits, and interventions may be targeted at any of these functions.
机译：本研究的目的是根据皮质-纹状体-丘脑-皮质（CSTC）神经回路的神经解剖学和神经生物学的进展，回顾和更新与边缘系统有关的历史争议。假设通过皮层下脑回路之间的过度交流，可以更好地理解观察到的内在性和外在性儿童综合症之间的合并症。对模块化电路之间的双向连接和非双向连接的神经解剖学理解，为理解先前令人费解的内在化和外在性合并症提供了基础。功能取决于目标定向，巴甫洛夫刺激反应和皮层-皮层下回路中的操作处理的协作整合程度，并且干预可能针对这些功能中的任何一种。

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