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Novel nanobiotechnological concepts in electrochemical biosensors for the analysis of toxins

机译:电化学生物传感器中用于毒素分析的新型纳米生物技术概念

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This article gives an overview of the biosensors for the analysis of mycotoxins, marine toxins and cyanobacterial toxins, describing in depth the electrochemical biosensors that incorporate nanobiotechnological concepts. Firstly, it presents tailor-designed biomolecules, such as recombinant enzymes, recombinant antibody fragments and aptamers as novel biorecognition elements in biosensors. It also reviews the use of metallic nanoparticles (NPs) and carbon nanotubes (CNTs) aiming at improving the electrochemical transduction strategies. Finally, the exploitation of magnetic particles (MPs) as immobilisation carriers in flow-systems and the development of arrays are also described. The incorporation of these nanobiotechnological concepts provides with electrochemical biosensors with superior analytical performance in terms of specificity, sensitivity, stability and analysis time. This journal is
机译:本文概述了用于分析霉菌毒素,海洋毒素和蓝细菌毒素的生物传感器,深入描述了结合了纳米生物技术概念的电化学生物传感器。首先,它提出了量身设计的生物分子,例如重组酶,重组抗体片段和适体,作为生物传感器中的新型生物识别元件。它还回顾了旨在改善电化学转导策略的金属纳米颗粒(NPs)和碳纳米管(CNTs)的使用。最后,还描述了利用磁性颗粒(MPs)作为流动系统中的固定载体以及阵列的开发。这些纳米生物技术概念的结合为电化学生物传感器提供了在特异性,灵敏性,稳定性和分析时间方面均具有出色的分析性能。这本日记是

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