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首页> 外文期刊>The Bovine Practitioner >Efficacy of an Arcanobacterium pyogenes-Fusobacterium necrophorum Bacterin-Toxoid as an Aid in the Prevention of Liver Abscesses in Feedlot Cattle
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Efficacy of an Arcanobacterium pyogenes-Fusobacterium necrophorum Bacterin-Toxoid as an Aid in the Prevention of Liver Abscesses in Feedlot Cattle

机译：化脓性产弧菌-坏死融合杆菌细菌-类毒素在预防饲养场牛肝脓肿中的功效

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Two studies were done to test the efficacy of a single-dose, bivalent Arcanobacterium pyogenes -Fusobacterium necrophorum bacterin-toxoid to reduce liver abscess prevalence and severity when given to cattle entering a feedlot. In each study, steers (~300/ treatment group) were randomized to pens and the pens randomly assigned to treatment groups, Treatment groups included 1) steers given a high-antigen dose bacterin-toxoid, 2) steers given a lower-antigen dose bacterin-toxoid, 3) steers fed tylosin-medicated feed, 4) control steers fed feed without tylosin, and in Study 2 only, 5) vaccinated steers fed tylosin-medicated feed. Steers were followed to slaughter and the liver abscesses scored, the USDA carcass and yield grades recorded, and the pen average daily gain and feed conversion calculated. Pen effects were not detected in the analysis of liver abscess prevalence data. A single vaccination with the high-antigen dose bacterin-toxoid reduced the prevalence of liver abscesses 48.4% (16% vaccinates vs 31% controls, P = 0.0001) in Study 1, and 37.5% (30% vaccinates vs 48% controls, P = 0.001) in Study 2.
机译：进行了两项研究，以测试单剂量，二价化脓性产Arcanobacterium pyogenes -Fusobacterium necrophorum bacterin-toxoid降低进入饲养场的牛的肝脓肿患病率和严重程度的功效。在每项研究中，将ste牛皮（〜300 /治疗组）随机分配到围栏，并将围栏随机分配到处理组。处理组包括1）给予高抗原剂量类毒素的ste牛皮，2）给予较低抗原剂量的ers牛皮细菌类毒素，3）饲喂泰乐菌素加药饲料的ers牛皮，4）对照饲喂不含泰乐菌素的饲料，仅在研究2中，5）接种了泰乐菌素加药的疫苗的ers牛皮。屠宰后跟踪牛，对肝脓肿评分，记录USDA car体和单产等级，并计算出平均日增重和饲料转化率。在肝脓肿患病率数据分析中未检测到笔作用。在研究1中，单次接种高抗原剂量的类细菌毒素可降低肝脓肿的患病率48.4％（16％的疫苗对31％的对照组，P = 0.0001）和37.5％（30％的疫苗对48％的对照，P） = 0.001）。

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