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首页> 外文期刊>The British journal of psychiatry : >Sustained attention and executive functions in euthymic young people with bipolar disorder.
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Sustained attention and executive functions in euthymic young people with bipolar disorder.

机译：在患有躁郁症的正常人中，持续的注意力和执行功能。

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BACKGROUND: Persistent neuropsychological impairments have been reported in the euthymic phase of bipolar affective disorder. However, the findings have been confounded by multiple episodes, chronic illness and residual mood symptoms. AIMS: To assess sustained attention and executive functioning in euthymic young people with bipolar I disorder who had had no more than two affective episodes. METHOD: Thirty euthymic patients (with illness duration of less than 5 years and no more than two affective episodes) and 30 matched healthy individuals were assessed for sustained attention and executive functioning. RESULTS: The bipolar group (mean age 22.4 years, s.d.=2.52; duration of illness 20.87 months, s.d.=14.72), showed impairment on tasks of attention and executive functioning. Multivariate logistic regression analysis demonstrated that deficits in executive functioning differentiated cases from controls. There was no correlation between residual depressive symptoms and neuropsychological performance. CONCLUSIONS: Deficits in attention and executive functioning were present in young people who had experienced only a few episodes of bipolar disorder, suggesting that the deficits are possibly trait abnormalities. Whether these deficits worsen with progression of illness needs to be examined in longitudinal studies.
机译：背景：在双相情感障碍的正常阶段，已有持续性神经心理障碍的报道。然而，这些发现被多种发作，慢性病和残留的情绪症状所混淆。目的：评估患有躁郁症I型情感异常的年轻人的持续注意力和执行功能，他们的情感发作不超过两次。方法：对30名正常患者（病程少于5年且不超过2次情感发作）和30名匹配的健康个体进行持续关注和执行功能评估。结果：双相情感障碍组（平均年龄22.4岁，标准误= 2.52;病程20.87个月，标准误14.72）在注意力和执行功能方面表现出障碍。多变量logistic回归分析表明，执行功能的缺陷使病例与对照有所区别。残余的抑郁症状与神经心理表现之间没有相关性。结论：仅经历了少数躁郁症发作的年轻人存在注意力和执行功能的缺陷，这表明缺陷可能是性状异常。这些缺陷是否随着疾病的进展而恶化，需要在纵向研究中进行研究。

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