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Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys

机译:世卫组织世界心理健康调查中的童年逆境和成人心理病理学

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摘要

Background Although significant associations of childhood adversities with adult mental disorders are widely documented, most studies focus on single childhood adversities predicting single disorders. Aims To examine joint associations of 12 childhood adversities with first onset of 20 DSM-IV disorders in World Mental Health (WMH) Surveys in 21 countries. Method Nationally or regionally representative surveys of 51945 adults assessed childhood adversities and lifetime DSM-IV disorders with the WHO Composite International Diagnostic interview (CIDI). Results Childhood adversities were highly prevalent and interrelated. Childhood adversities associated with maladaptive family functioning (e.g. parental mental illness, child abuse, neglect) were the strongest predictors of disorders. Co-occurring childhood adversities associated with maladaptive family functioning had significant subadditive predictive associations and little specificity across disorders. Childhood adversities account for 29.8% of all disorders across countries. Conclusions Childhood adversities have strong associations with all classes of disorders at all life-course stages in all groups of WMH countries. Long-term associations imply the existence of as-yet undetermined mediators.
机译:背景技术尽管广泛报道了儿童期逆境与成人精神障碍的显着相关性,但大多数研究集中在预测单一性疾患的单一儿童期逆境。目的在21个国家的世界心理健康(WMH)调查中,检查12种儿童逆境与20种DSM-IV疾病首次发作的联合关联。方法通过WHO综合国际诊断访谈(CIDI)对51945名成年人进行的全国或地区代表性调查评估了儿童的逆境和终生DSM-IV疾病。结果儿童时期的逆境非常普遍且相互关联。与适应不良的家庭功能有关的童年逆境(例如父母的精神疾病,虐待儿童,忽视)是最有可能预测疾病的指标。与适应不良的家庭功能相关的儿童期并发逆境具有显着的亚可加预测性关联,并且跨疾病的特异性很小。儿童逆境占所有国家所有疾病的29.8%。结论在WMH国家的所有群体中,儿童的逆境与生活过程各个阶段的各类疾病都有很强的联系。长期联系意味着还存在尚未确定的调解人。

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