Grey-matter abnormalities in boys with Tourette syndrome: magnetic resonance imaging study using optimised voxel-based morphometry.

Ludolph AG; Juengling FD; Libal G; Ludolph AC; Fegert JM; Kassubek J

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Grey-matter abnormalities in boys with Tourette syndrome: magnetic resonance imaging study using optimised voxel-based morphometry.

机译：Tourette综合征男孩的灰色物质异常：使用基于体素的最佳形态计量学的磁共振成像研究。

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The genesis of Tourette syndrome is still unknown, but a core role for the pathways of cortico-striatal-thalamic-cortical circuitry (CSTC) is supposed. Volume-rendering magnetic resonance imaging data-sets were analysed in 14 boys with Tourette syndrome and 15 age-matched controls using optimised voxel-based morphometry. Locally increased grey-matter volumes (corrected P<0.001) were found bilaterally in the ventral putamen. Regional decreases in grey matter were observed in the left hippocampal gyrus. This unbiased analysis confirmed an association between striatal abnormalities and Tourette syndrome, and the hippocampal volume alterations indicate an involvement of temporolimbic pathways of the CSTC in the syndrome.

机译：抽动秽语综合征的起源仍然是未知的，但应该假定其是皮质-纹状体-丘脑-皮质回路（CSTC）通路的核心作用。使用优化的基于体素的形态学方法，对14位患有Tourette综合征的男孩和15位年龄相匹配的对照进行了体绘制磁共振成像数据集的分析。在腹侧壳中双侧发现局部增加的灰质体积（校正后的P <0.001）。在左海马回中观察到灰质的区域减少。这项无偏见的分析证实了纹状体异常和Tourette综合征之间的关联，并且海马体量的变化表明CSTC的颞下颌骨通路参与了该综合征。

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《The British journal of psychiatry :》 |2006年第0期|共2页
作者
Ludolph AG; Juengling FD; Libal G; Ludolph AC; Fegert JM; Kassubek J;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Tourette Syndrome; Morphometric analysis; NOS; Magnetic Resonance Imaging; 多动秽语综合征; 磁共振成像;

机译：Tourette Syndrome;Morphometric analysis;NOS;Magnetic Resonance Imaging;多动秽语综合征;磁共振成像;

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1. Grey-matter abnormalities in boys with Tourette syndrome: magnetic resonance imaging study using optimised voxel-based morphometry. [J] . Ludolph AG, Juengling FD, Libal G, The British journal of psychiatry : . 2006,第0期

机译：Tourette综合征男孩的灰色物质异常：使用基于体素的最佳形态计量学的磁共振成像研究。
2. No brain structure abnormalities in boys with Tourette's syndrome: A voxel-based morphometry study [J] . RoessnerV., OverlackS., BaudewigJ., Movement disorders . 2009,第16期

机译：图雷特氏综合症男孩中没有脑结构异常：一项基于体素的形态计量学研究
3. A magnetic resonance imaging study of patients with Parkinson's disease with mild cognitive impairment and dementia using voxel-based morphometry. [J] . Beyer MK, Janvin CC, Larsen JP, Journal of Neurology, Neurosurgery and Psychiatry . 2007,第3期

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4. Voxel-Based Morphometric Study of Brain Regions from Magnetic Resonance Images in Temporal Lobe Epilepsy [C] . Matineh Shaker, Hamid Soltanian-Zadeh IEEE Southwest Symposium on Image Analysis Interpretation . 2008

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5. Combined application of voxel-based morphometry and magnetization transfer ratio for group analysis of magnetic resonance images [D] . Woo, Vivian 2006

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6. PS174. Possible involvement of rumination in gray matter abnormalities in persistent symptoms of major depression: an exploratory magnetic resonance imaging voxel-based morphometry study [O] . Ahiko Machino, Tomoya Matsumoto, Shigeto Yamawaki 2016

机译：PS174。重症抑郁症持续症状中灰质反刍可能涉及反刍：基于体素的探索性磁共振成像形态学研究
7. Grey-matter abnormalities in boys with Tourette syndrome: magnetic resonance imaging study using optimised voxel-based morphometry [O] . Ludolph, Andrea G, Juengling, Freimut D, Libal, Gerhard, 2006

机译：Tourette综合征男孩的灰色物质异常：使用基于体素的最佳形态计量学的磁共振成像研究

Grey-matter abnormalities in boys with Tourette syndrome: magnetic resonance imaging study using optimised voxel-based morphometry.

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