Intellectual asymmetry and genetic liability in first-degree relatives of probands with schizophrenia.

Kravariti E; Toulopoulou T; Mapua Filbey F; Schulze K; Walshe M; Sham P; Murray RM; McDonald C

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Intellectual asymmetry and genetic liability in first-degree relatives of probands with schizophrenia.

机译：精神分裂症先证者一级亲属的智力不对称和遗传责任。

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Intellectual asymmetry with superiority of verbal skills to spatial skills frequently characterises patients with schizophrenia, but it is unclear whether this pattern also reflects genetic susceptibility to the disorder. We examined the association of a continuous measure of genetic liability to schizophrenia with Verbal-Spatial Contrast IQ (an index of intellectual asymmetry) in 108 first-degree relatives without psychosis of probands with schizophrenia. Higher genetic liability was significantly associated with greater intellectual asymmetry in favour of verbal skills. Intellectual asymmetry with a relative superiority of verbal skills to spatial skills represents a putative endophenotype of schizophrenia.

机译：精神分裂症患者经常表现出智力上的不对称，其口头表达能力优于空间表达能力，但尚不清楚这种模式是否也反映出该疾病的遗传易感性。我们检查了108名一级无精神分裂症先证者的亲属的精神分裂症遗传责任的连续测量与言语-空间对比智商（智力不对称指数）的关联。更高的遗传责任感与更大的智力不对称显着相关，有利于口头表达能力。智力不对称具有相对于空间技能而言的口头表达能力优势，这代表了精神分裂症的一种内在表型。

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《The British journal of psychiatry :》 |2006年第0期|共2页
作者
Kravariti E; Toulopoulou T; Mapua Filbey F; Schulze K; Walshe M; Sham P; Murray RM; McDonald C;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Schizophrenia; skills; Genetic; Proband; Academic degree; 精神分裂症;

机译：Schizophrenia;skills;Genetic;Proband;Academic degree;精神分裂症;

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1. Intellectual asymmetry and genetic liability in first-degree relatives of probands with schizophrenia. [J] . Kravariti E, Toulopoulou T, Mapua Filbey F, The British journal of psychiatry : . 2006,第0期

机译：精神分裂症先证者一级亲属的智力不对称和遗传责任。
2. Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia. [J] . Horan WP, Braff DL, Nuechterlein KH, Schizophrenia research . 2008,第1a3期

机译：精神分裂症患者及其一级亲属的口头工作记忆障碍：精神分裂症遗传学联合会的发现。
3. Links between looking and speaking in autism and first-degree relatives: insights into the expression of genetic liability to autism [J] . Kritika Nayar, Peter C Gordon, Gary E Martin, Molecular Autism . 2018,第1期

机译：在自闭症和一级亲属的看和发言之间的联系：洞察遗传责任对自闭症的表达
4. Voluntary Disclosure of Intellectual Assets and Intellectual Liabilities: A Literature Review [C] . George Majdalany, Armond Manassian European Conference on Intellectual Capital . 2012

机译：自愿披露知识产权和智力负债：文献综述
5. Behavioral and Electrophysiological Correlates of Context Processing in Individuals with Schizophrenia and Their First-Degree Relatives. [D] . Jones, Jessica Ann Hurdelbrink. 2011

机译：精神分裂症患者及其一级亲属的情境处理的行为和电生理相关性。
6. Executive Function in Autism Probands With Average Intellectual Ability and Their Unaffected First-Degree Relatives [O] . Rebecca L. McLean, Ashley J. Johnson, Eric Zimak, -1

机译：具有平均智力水平的自闭症先证者的执行功能及其未受影响的一等亲戚
7. Intellectual asymmetry and genetic liability in first-degree relatives of probands with schizophrenia [O] . Kravariti, E, Toulopoulou, T, Mapua-Filbey, F, 2006

机译：精神分裂症先证者一级亲属的智力不对称和遗传责任

Intellectual asymmetry and genetic liability in first-degree relatives of probands with schizophrenia.

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