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Efficacy of cognitive-behavioural therapy and other psychological treatments for adult depression: meta-analytic study of publication bias

机译:认知行为疗法和其他心理疗法对成人抑郁症的疗效:出版物偏倚的荟萃分析研究

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BackgroundIt is not clear whether the effects of cognitive-behavioural therapy and other psychotherapies have been overestimated because of publication bias.AimsTo examine indicators of publication bias in randomised controlled trials of psychotherapy for adult depression.MethodWe examined effect sizes of 117 trials with 175 comparisons between psychotherapy and control conditions. As indicators of publication bias we examined funnel plots, calculated adjusted effect sizes after publication had been taken into account using Duval & Tweedie's procedure, and tested thesymmetry of the funnel plots using the Begg & Mazumdar rank correlation test and Egger's test.ResultsThe mean effect size was 0.67, which was reduced after adjustment for publication bias to 0.42 (51 imputed studies). Both Begg & Mazumbar's test and Egger's test were highly significant (P<0.001).ConclusionsThe effects of psychotherapy for adult depression seem to be overestimated considerably because of publication bias.
机译:背景目前尚不清楚是否由于出版偏倚而高估了认知行为疗法和其他心理疗法的效果。目的探讨成人抑郁症心理治疗随机对照试验中的出版偏倚指标。方法:我们调查了117项试验的效果量,其中175项作了比较心理治疗和控制条件。作为发布偏倚的指标,我们检查了漏斗图,使用Duval&Tweedie的方法考虑了发布后的调整后效应大小,并使用Begg&Mazumdar秩相关检验和Egger检验测试了漏斗图的对称性。是0.67,在将发布偏倚调整为0.42后减少了(51推算研究)。 Begg&Mazumbar检验和Egger检验均具有高度显着性(P <0.001)。结论由于出版偏倚,心理疗法对成人抑郁症的效果似乎被高估了。

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