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首页> 外文期刊>The British journal of cardiology >Dabigatran improves the efficiency of an elective direct current cardioversion service
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Dabigatran improves the efficiency of an elective direct current cardioversion service

机译：达比加群提高了选择性直流电复律服务的效率

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摘要

Anticoagulation prior to direct current cardioversion (DCCV) is mandatory to reduce the risk of thromboembolism. We examined the impact of the use of dabigatran as an alternative to warfarin on the efficiency of an outpatient DCCV service. A total of 242 DCCVs performed on 193 patients over a 36-month period were analysed. Patients were divided into two cohorts; cohort A included cases in the 22-month period before the introduction of dabigatran and cohort B included cases in the 14-month period after the introduction of dabigatran. All patients in cohort A received warfarin. In cohort B, 48.4% received dabigatran. A larger number of patients from cohort A were rescheduled due to subtherapeutic international normalised ratios (INRs) compared with cohort B (42.1% vs. 15.6%, p<0.001). Those who received dabigatran had significantly lower rates of rescheduling compared with those who received warfarin (9.7% vs. 34.4%, p<0.001). The length of time between initial assessment and DCCV was 24 days shorter in cohort B than cohort A (p<0.001) and 22 days shorter with those who took dabigatran than warfarin (p=0.0015). Outcomes in achieving and maintaining sinus rhythm were comparable in both cohorts and anticoagulants (all p>0.05). This study demonstrates that the use of dabigatran can improve the efficiency of an elective DCCV service.
机译：直流电复律（DCCV）前必须进行抗凝治疗，以减少血栓栓塞的风险。我们研究了使用达比加群替代华法林对门诊DCCV服务效率的影响。分析了在36个月内对193例患者进行的242例DCCV。患者分为两组。队列A包括达比加群引入前22个月的病例，队列B包括达比加群引入后14个月的病例。 A组的所有患者均接受了华法林治疗。在队列B中，有48.4％的患者接受了达比加群治疗。与亚组B相比，由于亚治疗国际标准化比率（INRs），有更多的A组患者被重新安排（42.1％vs. 15.6％，p <0.001）。与接受华法林的患者相比，接受达比加群治疗的患者的改期率显着降低（9.7％比34.4％，p <0.001）。 B组的初始评估与DCCV之间的时间比A组的短24天（p <0.001），而服用达比加群的患者比Warfarin的短22天（p = 0.0015）。在队列研究和抗凝治疗方面，实现和维持窦性心律的结果相当（所有p> 0.05）。这项研究表明，达比加群的使用可以提高DCCV选择性服务的效率。

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