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首页> 外文期刊>The European Journal of Neuroscience >Ultrastructural characterization of the mesostriatal dopamine innervations in mice, including two mouse lines of conditional VGLUT2 knockout in dopamine neurons
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Ultrastructural characterization of the mesostriatal dopamine innervations in mice, including two mouse lines of conditional VGLUT2 knockout in dopamine neurons

机译：小鼠中肋多巴胺神经支配的超微结构表征，包括多巴胺神经元中条件性VGLUT2基因敲除的两条小鼠系

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Fig. 2. DA terminals from the NAC in P15 or adult control and Vglut2 cKO mice. As illustrated in this and the following figures, the TH-immu-nolabeled terminals (varicosities) in NAC (Figs 2 and 5) and NAS (Fig. 3), as well as in NS (Fig. 4), share similar ultrastructural features, whether in control or Vglutl cKO mice of both ages (see also Tables 1 and 2). These varicosities are relatively small, generally round or ovoid in shape, filled with small vesicles and associated or not with mitochondria, and the vast majority are without apparent synaptic membrane specialization (junc-tional complex). (A, C and D) Rare examples of TH-labeled synaptic varicosities, most of which form small, symmetrical junctions (between small arrows) with dendritic branches (db). (B, E and E') More typical examples of asynaptic terminals.
机译：图2.来自P15或成年对照和Vglut2 cKO小鼠中NAC的DA末端。如该图和下图所示，NAC（图2和5）和NAS（图3）以及NS（图4）中TH-免疫标记的末端（粘度）具有相似的超微结构特征，无论是在两个年龄段的对照小鼠还是Vglutl cKO小鼠中（另请参见表1和2）。这些静脉曲张相对较小，通常为圆形或卵形，充满小囊泡，与线粒体相关或不相关，并且绝大多数没有明显的突触膜特化（结缔复合体）。 （A，C和D）TH标记的突触静脉曲张的稀有例子，其中大多数形成带有树突分支（db）的小的对称连接（在小箭头之间）。 （B，E和E'）更多典型的突触末端例子。

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