首页> 外文期刊>The European Journal of Neuroscience >Impairment of binocular vision in the adult cat induces plastic changes in the callosal cortical map.
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Impairment of binocular vision in the adult cat induces plastic changes in the callosal cortical map.

机译:成年猫的双眼视力障碍会引起al骨皮质图的塑性变化。

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In the primary visual cortex of normally reared adult cat, neurons activated through the corpus callosum are almost entirely located at the 17/18 border. They display small receptive fields distributed along the central vertical meridian of the visual field and are orientation selective. Here we demonstrate that a few weeks of monocular deprivation or unilateral convergent strabismus produced in adulthood does not modify the cortical distribution of these neurons, but leads to an increase of their receptive field size mainly toward the ipsilateral hemifield and to a loss of their orientation selectivity. We conclude that manipulation of binocular vision in the adult modifies neither the location of the primary callosal cortical map nor its retinotopy. In contrast, it induces functional plastic changes in this map which lead to a significant widening of the area of visual space signalled through the corpus callosum. These plastic changes are interpreted as the result of the strengthening of normally hidden subthreshold synaptic inputs.
机译:在正常饲养的成年猫的主要视觉皮层中,通过call体激活的神经元几乎完全位于17/18边界。它们显示出沿视场中央垂直子午线分布的小的感受野,并且具有方向选择性。在这里,我们证明成年后产生的单眼剥夺或单侧会聚性斜视不会改变这些神经元的皮质分布,但会导致它们对主要同侧半野的感受野增大,并导致其方向选择性的丧失。我们得出的结论是,在成年人中双目视觉的操纵既不会改变主视call皮质图的位置,也不会改变其视视网膜的位置。相反,它在该图谱中引起功能性塑性变化,从而导致通过the体发出的视觉空间区域显着扩大。这些可塑性变化被解释为增强了通常隐藏的阈下亚突触输入的结果。

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