Transistor array with an organotypic brain slice: field potential records and synaptic currents.

Besl B; Fromherz P

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Transistor array with an organotypic brain slice: field potential records and synaptic currents.

机译：具有器官型脑片的晶体管阵列：场电势记录和突触电流。

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Linear transistor arrays on a silicon chip were used to map evoked extracellular field potentials in organotypic brain slices of rat hippocampus. The shape and amplitude of the transients were similar to those from records with micropipette electrodes. The spatial resolution was 21 and 4.6 microm. The sampled profile of the field potential showed a wide and shallow trough of transients in the stratum radiatum and a narrow but higher ridge in the stratum pyramidale. Due to the high resolution, the profile could be interpreted quantitatively in terms of synaptic currents. Transistor chips may become a novel tool for neurophysiological and pharmacological studies in brain slices.

机译：硅芯片上的线性晶体管阵列用于绘制大鼠海马器官型脑切片中诱发的细胞外场电位。瞬态的形状和幅度类似于用微量移液器电极记录的瞬态的形状和幅度。空间分辨率为21和4.6微米。采样的场势剖面表明，在辐射层中有一个宽而浅的波谷，在金字塔状层中有一个狭窄但较高的山脊。由于具有高分辨率，因此可以根据突触电流定量地解释轮廓。晶体管芯片可能成为脑片神经生理学和药理学研究的一种新型工具。

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来源
《The European Journal of Neuroscience》 |2002年第6期|共7页
作者
Besl B; Fromherz P;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Electrophysiology; Evoked Potentials; Hippocampus; Microelectrodes; Neurons; 电生理学; 诱发电位; 海马; 微电极; 神经元; 器官培养; 突触传递; 晶体管;

机译：Electrophysiology;Evoked Potentials;Hippocampus;Microelectrodes;Neurons;电生理学;诱发电位;海马;微电极;神经元;器官培养;突触传递;晶体管;

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1. Transistor array with an organotypic brain slice: field potential records and synaptic currents. [J] . Besl B, Fromherz P The European Journal of Neuroscience . 2002,第6期

机译：具有器官型脑片的晶体管阵列：场电势记录和突触电流。
2. High-resolution multitransistor array recording of electrical field potentials in cultured brain slices. [J] . Hutzler M, Lambacher A, Eversmann B, Journal of Neurophysiology . 2006,第3期

机译：高分辨率多晶体管阵列记录培养的脑片中电场电位。
3. Neuronal field potential in acute hippocampus slice recorded with transistor and micropipette electrode. [J] . Stangl C, Fromherz P The European Journal of Neuroscience . 2008,第4期

机译：用晶体管和微量移液器电极记录急性海马切片中的神经元场电位。
4. Probing Extracellular Matrix Structural Changes in Organotypic Rat Brain Slices using Multiple Particle Tracking [C] . Mike McKenna, Hugo Pontes, Elizabeth Nance Society for Biomaterials annual meeting and exposition . 2019

机译：使用多个粒子跟踪探测器官型大鼠脑切片中的细胞外基质结构变化。
5. Cellular physiology and synaptic pharmacology of the rat's external cortex of the inferior colliculus studied using in vitro brain slice techniques. [D] . Ahuja, Tarun Kumar. 2004

机译：使用体外脑切片技术研究大鼠下丘脑外皮层的细胞生理学和突触药理学。
6. Large-scale high-resolution electrophysiological imaging of field potentials in brain slices with microelectronic multielectrode arrays [O] . E. Ferrea, A. Maccione, L. Medrihan, 2012

机译：微电子多电极阵列的脑切片中场电位的大规模高分辨率电生理成像
7. Large-scale, high-resolution electrophysiological imaging of field potentials in brain slices with microelectronic multielectrode arrays [O] . E. Ferrea, A. Maccione, L. Medrihan, 2012

机译：微电子多电极阵列的脑切片中场电位的大规模，高分辨率电生理成像
8. Differential Conditioning of Associative Synaptic Enhancement in Hippocampal Brain Slices [R] . Kelso, S. R., Brown, T. H. 1986

机译：海马脑片联合突触增强的差异调节

Transistor array with an organotypic brain slice: field potential records and synaptic currents.

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