• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The European Journal of Neuroscience >Task-induced modulation of motor evoked potentials in upper-leg muscles during human gait: a TMS study.
【24h】

Task-induced modulation of motor evoked potentials in upper-leg muscles during human gait: a TMS study.

机译：TMS研究：在人的步态中任务诱发的大腿肌肉运动诱发电位的调制。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The aim of this study was to determine the relative involvement of the corticospinal (CS) pathway in voluntarily controlled walking compared to unconstrained walking. In the voluntarily controlled walking condition, subjects had to walk at the same speed as in unconstrained walking with a mechanical constraint, which is known to affect specifically the upper-leg muscles. The motor cortex was activated transcranially using a focal magnetic stimulation coil in order to elicit motor evoked potentials (MEPs) in the rectus femoris (RF) and the biceps femoris (BF). The magnetic stimulation was delivered at the end of the swing (at 90% of the cycle duration), when the EMG backgrounds were similar in the two experimental conditions. For each subject in each condition, MEPs were measured for several stimulus intensities in order to establish the input/output (I/O) curve (MEPs amplitude plotted against stimulus strength). The results showed a significant increase in the MEPs amplitude of both the RF and BF in voluntarily controlled walking compared to unconstrained walking, which is the first evidence of cofacilitation of MEPs in antagonist upper-leg muscles during human gait. In conclusion, although a lot of studies have emphasized a privileged input of the corticospinal pathway to the distal lower-leg muscles, this study shows that, if a locomotory task requires fine control of the proximal upper-leg muscles, a selective facilitation of MEPs is observed in these muscles.
机译：这项研究的目的是确定与无约束步行相比，皮质脊髓（CS）通路在自愿控制步行中的相对参与度。在自愿控制的步行条件下，受试者必须以与无约束步行相同的速度行走，并受到机械约束，已知这会特别影响大腿肌肉。运动皮层使用聚焦磁刺激线圈经颅激活，以引起股直肌（RF）和股二头肌（BF）的运动诱发电位（MEP）。当两个实验条件下的肌电图背景相似时，在挥杆结束时（周期持续时间的90％）进行磁刺激。对于每种情况下的每个受试者，测量MEP的几种刺激强度，以建立输入/输出（I / O）曲线（MEP幅度与刺激强度的关系图）。结果表明，与无约束步行相比，在自愿控制步行中，RF和BF的MEP幅度显着增加，这是在步态中辅助大腿肌肉中MEP协同作用的第一个证据。总之，尽管许多研究都强调了皮质脊髓通路向小腿远端肌肉的特权输入，但这项研究表明，如果运动任务需要对小腿近端肌肉进行精细控制，则选择性促进MEPs在这些肌肉中观察到。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号