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首页> 外文期刊>The European Journal of Neuroscience >Dynamic increases in dopamine during paced copulation in the female rat.
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Dynamic increases in dopamine during paced copulation in the female rat.

机译：在雌性大鼠的定律交配过程中多巴胺的动态增加。

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摘要

The role of dopamine in the rewarding aspects of sexual behaviour in female rats was investigated. This is a unique model because sexual behaviour is only rewarding when copulatory stimuli are experienced at the preferred rate of copulation for a female rat. In addition, increases in dopamine in the nucleus accumbens occur during sexual behaviour only when the female achieves this preferred rate of copulation. In this study, minute-by-minute changes in nucleus accumbens dopamine were monitored using in vivo microdialysis. We report here that extracellular dopamine in the nucleus accumbens increases before coital stimulation only when sexual behaviour is occurring under conditions that are rewarding to the female rat. We conclude that increases in dopamine in the nucleus accumbens are involved in anticipation, not consummation, of sexual behaviour in the female rat.
机译：研究了多巴胺在雌性大鼠性行为的奖励方面的作用。这是一个独特的模型，因为只有在雌性大鼠以最佳的交配速率经历交配刺激时，性行为才有意义。另外，仅当女性达到该优选的交配率时，伏隔核中多巴胺的增加才发生。在这项研究中，使用体内微透析监测伏隔核多巴胺的每分钟变化。我们在这里报告仅在性行为在对雌性大鼠有益的条件下发生时，在性交刺激之前，伏隔核中的细胞外多巴胺会增加。我们得出结论，伏隔核中多巴胺的增加与雌性大鼠性行为的预期而非完善有关。

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