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首页> 外文期刊>The European Journal of Neuroscience >Characterization of the human visual V6 complex by functional magnetic resonance imaging.
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Characterization of the human visual V6 complex by functional magnetic resonance imaging.

机译：通过功能磁共振成像表征人类视觉V6复合物。

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Magnetoencephalography of a visual area along the human parieto-occipital sulcus suggested that this region represents the human homologue of the monkey visual area V6 complex (visual area V6/visuomotor area V6A) involved in the integration of visual and somatomotor information. We used functional magnetic resonance imaging at 2.0 T and 2 x 2 x 3 mm3 resolution (16 sections) to characterize visual areas along the parieto-occipital sulcus in five healthy human subjects. Paradigms comprised a full-field checkerboard stimulation, a full-field luminance flicker as well as a foveal and peripheral luminance flicker using both a direct and differential design for comparing functional states. Along the parieto-occipital sulcus, and in contrast to primary visual areas, luminance stimulation evoked much larger activation volumes than checkerboard stimulation. Moreover, based on anatomic landmarks, luminance stimulation identified two functionally distinct regions of parieto-occipital sulcus activations: an inferior part (supposedly visual area V6) and a superior portion (supposedly visuomotor area V6A). With these assignments, foveal vs. peripheral luminance stimulation revealed a weaker foveal overrepresentation in visual area V6/visuomotor area V6A than in early visual areas, and only a mild tendency for a retinotopic organization in visual area V6. Further analyses of the functional coding of the human visual area V6 complex require functional magnetic resonance imaging at even higher spatial resolution.
机译：沿人顶枕沟的视觉区域的磁脑图表明，该区域代表猴子视觉区域V6复合体（视觉区域V6 /视觉运动区域V6A）的人类同源物，涉及视觉和躯体运动信息的整合。我们以2.0 T和2 x 2 x 3 mm3的分辨率（16个部分）使用功能磁共振成像来表征五名健康人类受试者沿着顶枕沟的视觉区域。范例包括全场棋盘刺激，全场亮度闪烁以及中央凹和周围亮度闪烁，使用直接和差分设计来比较功能状态。沿着顶枕沟，与主要视觉区域相反，亮度刺激引起的激活量比棋盘刺激大得多。此外，基于解剖标志，亮度刺激确定了顶枕沟激活的两个功能上不同的区域：下半部分（假定为视觉区域V6）和上半部分（假定为视运动区域V6A）。通过这些分配，中央凹vs.周边亮度刺激显示，在视觉区域V6 /视觉运动区域V6A中，中央凹的中央凹过度表达较早期视觉区域弱，而在视觉区域V6中仅存在轻微的视网膜组织变化趋势。对人类视觉区域V6复合体的功能编码的进一步分析要求以更高的空间分辨率进行功能磁共振成像。

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