GABA-immunoreactive starburst amacrine cells in pigmented and albino rats.

Blaszczyk WM; Telkes I; Distler C

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GABA-immunoreactive starburst amacrine cells in pigmented and albino rats.

机译：有色和白化病大鼠的GABA免疫反应性星爆无长突细胞。

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In this study we tested whether the critical anatomical substrate for retinal direction selectivity is altered in albino mammals. We used dual immunostaining for GABA and choline acetyltransferase and quantitatively analyzed the number of double-labelled starburst amacrine cells in wild-type and albino rats. In albino rats, the percentage of ON-amacrine cells with high GABA content was significantly lower than in pigmented animals. OFF-amacrines did not significantly differ between the two rat strains. Thus, the decreased GABA content in ON-amacrine cells could reflect an altered neuronal substrate for retinal direction selectivity. These results are discussed in relation to the optokinetic deficits described in albino mammals.

机译：在这项研究中，我们测试了在白化病哺乳动物中视网膜方向选择性的关键解剖底物是否发生了改变。我们对GABA和胆碱乙酰转移酶进行了双重免疫染色，并定量分析了野生型和白化病大鼠中双标记星状突突无长突细胞的数量。在白化病大鼠中，具有高GABA含量的ON-amacrine细胞的百分比明显低于有色动物。在两个大鼠品系之间，OFF-金刚烷没有显着差异。因此，ON-amacrine细胞中GABA含量的降低可能反映了神经元底物对视网膜方向选择性的改变。关于白化病哺乳动物中描述的视动学缺陷讨论了这些结果。

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《The European Journal of Neuroscience》 |2004年第11期|共4页
作者
Blaszczyk WM; Telkes I; Distler C;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Amacrine Cells; gamma-Aminobutyric Acid; albino rat; Retinaldehyde; 视网膜醛;

机译：Amacrine Cells;gamma-Aminobutyric Acid;albino rat;Retinaldehyde;视网膜醛;

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1. SP-8-CPT-cAMP对神经节细胞和无长突细胞间示踪剂藕连的影响 [J] . 夏晓波, 周霞, Stephen L Mills 眼科学报（英文版） . 2003,第002期
2. GABA-immunoreactive starburst amacrine cells in pigmented and albino rats. [J] . Blaszczyk WM, Telkes I, Distler C The European Journal of Neuroscience . 2004,第11期

机译：有色和白化病大鼠的GABA免疫反应性星爆无长突细胞。
3. Symmetric interactions within a homogeneous starburst cell network can lead to robust asymmetries in dendrites of starburst amacrine cells. [J] . Munch TA, Werblin FS Journal of Neurophysiology . 2006,第1期

机译：均匀的爆炸形细胞网络内的对称相互作用可导致爆炸形无长突细胞的树突中出现强烈的不对称性。
4. A structural basis for omnidirectional connections between starburst amacrine cells and directionally selective ganglion cells in rabbit retina, with associated bipolar cells. [J] . Famiglietti EV Visual Neuroscience: An International Journal for Empirical and Theoretical Research . 2002,第2期

机译：兔视网膜星爆无长突细胞与定向选择性神经节细胞与相关双极细胞之间全向连接的结构基础。
5. A directionally-selective neuromorphic circuit based on reciprocal synapses in Starburst Amacrine Cells [C] . Tseng Ko-Chung, Parker Alice C., Joshi Jonathan 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2011

机译：基于相互突触的星爆无长突细胞定向定向神经形态电路
6. Network properties of starburst amacrine cells during development and in visual processing. [D] . Lee, Seunghoon. 2005

机译：星爆无长突细胞在发育和视觉加工过程中的网络特性。
7. Dendritic relationship between starburst amacrine cells and direction-selective ganglion cells in the rabbit retina [O] . Wei Dong, Wenzhi Sun, Yingye Zhang, 2004

机译：兔视网膜星爆无长突细胞与方向选择神经节细胞的树突关系
8. Whole number, distribution and co-expression of brn3 transcription factors in retinal ganglion cells of adult albino and pigmented rats. [O] . Francisco M Nadal-Nicolás, Manuel Jiménez-López, Manuel Salinas-Navarro, 2012

机译：成年白化病和色素沉着大鼠视网膜神经节细胞中brn3转录因子的总数，分布和共表达。

GABA-immunoreactive starburst amacrine cells in pigmented and albino rats.

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