首页> 外文期刊>The European Journal of Neuroscience >Enhanced mismatch negativity brain response after binaural word presentation.
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Enhanced mismatch negativity brain response after binaural word presentation.

机译:双耳单词呈现后增强的失配负性大脑反应。

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Abstract An oddball paradigm was used to investigate brain processes elicited by spoken words and pseudowords played monaurally, to the left or right ear, or simultaneously to both ears of human subjects instructed to ignore acoustic stimuli but watch a silent video film. The mismatch negativity (MMN), a neurophysiological index of the automatic activation of cortical memory traces, was calculated as the difference between the event-related potential elicited by an infrequent deviant stimulus and the event-related potential to the same item presented as a frequent standard stimulus. Consistent with earlier reports, the MMN to words was larger than that to pseudowords, possibly reflecting the existence of memory traces for spoken words. Bilateral redundant stimulus presentation led to a further increase of the MMN to words relative to both unilateral stimulation modes. This bilateral redundancy gain was absent for pseudowords. We interpret the neurophysiological manifestation of a word-specific bilateral redundancy gain as evidence for interhemispheric cooperation in the automatic access to memory traces for spoken words. Accordingly, word-related cortical networks distributed over both hemispheres allow summation of neural activity between and within hemispheres, thereby potentiating the word-related MMN.
机译:摘要:奇异球范式用于研究由单声道演奏的人说话的单词和假单词在左,右耳或同时在两只耳朵的双耳所引发的大脑过程,这些人被指示忽略听觉刺激但观看无声电影。失配阴性(MMN)是皮层记忆迹线自动激活的神经生理指标,其计算方法是:由不频繁的异常刺激引起的事件相关电位与频繁出现的同一项目的事件相关电位之间的差标准刺激。与早期的报告一致,对单词的MMN大于对伪单词的MMN,这可能反映了口语单词的存储轨迹的存在。相对于两种单边刺激模式,双边冗余刺激提示导致单词MMN的进一步增加。伪字不存在这种双边冗余增益。我们解释一个单词特定的双边冗余增益的神经生理学表现,作为自动访问口语单词记忆轨迹的半球合作的证据。因此,分布在两个半球上的与单词相关的皮质网络允许对半球之间和半球内的神经活动进行求和,从而增强了与单词相关的MMN。

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