Old ideas to innovate tuberculosis control: Preventive treatment to achieve elimination

DielR.; LoddenkemperR.; ZellwegerJ.-P.; SotgiuG.; DAmbrosioL.; CentisR.; VanDerWerfM.J.; DaraM.; DetjenA.; GondrieP.; ReichmanL.; BlasiF.; MiglioriG.B.

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Old ideas to innovate tuberculosis control: Preventive treatment to achieve elimination

机译：创新结核病控制的旧观念：预防性治疗以消除结核病

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The introduction of new rapid diagnostic tools for tuberculosis (TB) and the promising TB drugs pipeline together with the development of a new World Health Organization Strategy post 2015 allows new discussions on how to direct TB control. The European Respiratory Society's European Forum for TB Innovation was created to stimulate discussion on how to best take advantage of old and new opportunities, and advances, to improve TB control and eventually progress towards the elimination of TB. While TB control is aimed at reducing the incidence of TB by early diagnosis and treatment of infectious cases of TB, TB elimination requires focus on sterilising the pool of latently infected individuals, from which future TB cases would be generated. This manuscript describes the three core components that are necessary to implement the elimination strategy fully. 1) Improve diagnosis of latent TB infected individuals. 2) Improve regimens to treat latent TB infection. 3) ensure public health commitment to make both 1) and 2) possible. Old and new evidence is critically described, focusing on the European commitment to reach elimination and on the innovative experiences and best practices available.

机译：新的结核病快速诊断工具和有前途的结核病药物管道的引入，以及新的《 2015年后世界卫生组织战略》的制定，使得有关如何指导结核病控制的新讨论成为可能。创建了欧洲呼吸学会的欧洲结核病创新论坛，以激发人们就如何最好地利用新旧机遇和进步来改进结核病控制并最终在消除结核病方面取得进展的讨论。结核病控制旨在通过早期诊断和治疗结核病感染病例来减少结核病的发生，而结核病的消除则需要侧重于对潜伏感染者进行绝育，从而从中产生未来的结核病病例。该手稿描述了充分实施消除策略所必需的三个核心要素。 1）改善对潜伏性结核感染者的诊断。 2）改善治疗潜伏性结核感染的方案。 3）确保公共卫生承诺，使1）和2）成为可能。批判性地描述了新旧证据，重点是欧洲致力于消除污染的承诺以及现有的创新经验和最佳做法。

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《The European respiratory journal :》 |2013年第3期|共17页
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DielR.; LoddenkemperR.; ZellwegerJ.-P.; SotgiuG.; DAmbrosioL.; CentisR.; VanDerWerfM.J.; DaraM.; DetjenA.; GondrieP.; ReichmanL.; BlasiF.; MiglioriG.B.;
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中图分类呼吸系及胸部疾病;
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1. Old ideas to innovate tuberculosis control: Preventive treatment to achieve elimination [J] . DielR., LoddenkemperR., ZellwegerJ.-P., The European respiratory journal : . 2013,第3期

机译：创新结核病控制的旧观念：预防性治疗以消除结核病
2. Socioeconomic benefit to individuals of achieving 2020 targets for four neglected tropical diseases controlled/eliminated by innovative and intensified disease management: Human African trypanosomiasis, leprosy, visceral leishmaniasis, Chagas disease [J] . Edeltraud J. Lenk, William K. Redekop, Marianne Luyendijk, PLOS Neglected Tropical Diseases . 2018,第3期

机译：通过创新和强化疾病管理控制/消除的四种被忽视的热带疾病的个人的社会经济效益：人类非洲锥虫，麻风病，内脏Leishmaniaisis，Chagas病
3. Setting up the Goal of Eliminating Outbreaks of Blue-green Alga, Innovating the Idea of Controlling the Taihu Lake, and Ensuring the Safety of Water Supply in the Taihu Lake [J] . Xuqing CHEN, Jianhua MA, Xi ZHU 气象与环境研究：英文版 . 2020,第004期

机译：制定消除蓝绿藻爆发的目标，创新控制太湖湖的想法，并确保了太湖供水的安全性
4. INNOVATIVE DESIGN FOR CSO CONTROL AND TREATMENT An Innovative Design Featuring Vertical Treatment Shaft Achieves CSO Control Objectives at a Substantially Lower Cost, While Simplifying Operations [C] . James A. Heist, Robert Hawkins, Saad Ghalib, Collection Systems Conference . 2012

机译：用于CSO控制和处理的创新设计具有垂直处理轴的创新设计以相当低的成本实现了CSO控制目标，同时简化了运营
5. THE IDENTIFICATION AND PREVENTIVE TREATMENT OF POTENTIAL LOW ACADEMIC ACHIEVERS AND ACADEMIC DROPOUTS IN ELECTRICAL AND MECHANICAL TECHNOLOGY AT A COMMUNITY COLLEGE [D] . STILLERMAN, MANUEL. 1970

机译：社区高校机电技术专业中潜在低学业者和学业下降的识别和预防措施
6. MORE INNOVATIVE STRATEGIES NEEDED TO ACHIEVE THE GOAL OF TUBERCULOSIS ELIMINATION [O] . Hongling Xia 2005

机译：实现消除结核病目标所需的更多创新策略
7. Old ideas to innovate tuberculosis control: preventive treatment to achieve elimination [O] . Roland Diel, Robert Loddenkemper, Jean-Pierre Zellweger, 2013

机译：旧思想创新结核病控制：预防治疗实现消除
8. Morbidity and Mortality Weekly Report, May 3, 2002, Volume 51, Number RR-5. Progressing Toward Tuberculosis Elimination in Low-Incidence Areas of the United States. Recommendations of the Advisory Council for the Elimination of Tuberculosis [R] . 2002

机译：发病率和死亡率每周报告，2002年5月3日，第51卷，RR-5号。在美国低发病率地区消除结核病的进展。消除结核病咨询委员会的建议

Old ideas to innovate tuberculosis control: Preventive treatment to achieve elimination

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