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首页> 外文期刊>The European respiratory journal : >Same role and same treatment for airway eosinophilia in asthma and COPD? Society for Clinical Respiratory Physiology
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Same role and same treatment for airway eosinophilia in asthma and COPD? Society for Clinical Respiratory Physiology

机译：哮喘和COPD中气道嗜酸性粒细胞增多的作用和治疗相同吗？临床呼吸生理学会

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摘要

Chronic inflammatory diseases of the airway, such as asthma and chronic obstructive pulmonary disease (COPD), are common and represent a substantial amount of the workload of most respiratory physicians. While medications for asthma provide good control of the disease in the majority of cases , pharmacotherapy for COPD is less satisfactory since none of the existing drugs has been shown to have a significant effect on the long-term decline in lung function that is the hallmark of this disease . It is, however, underlined in the international guidelines that COPD is. a treatable disease , Current strategy in managing stable COPD includes several individualised interventions directed at different aspects of the disease. Most of these interventions are nonpharmacological, such as smoking cessation to prevent the accelerated loss of lung function, influenza and pneumococcal vaccines to prevent respiratory infections, exercise training to improve exercise tolerance and dyspnoea, nutritional support to avoidweight loss, and long-term administration of oxygen to increase survival in patients with chronic respiratory failure. Pharmacotherapy with long-acting bronchodilators is used to reduce symptoms and exacerbations. The addition of inhaled corticosteroids further reduces the frequency of exacerbations in patients with severe COPD .
机译：气道的慢性炎性疾病，例如哮喘和慢性阻塞性肺疾病（COPD），很常见，并且代表了大多数呼吸内科医师的大量工作量。尽管在大多数情况下，用于哮喘的药物可很好地控制该疾病，但用于COPD的药物治疗效果较差，因为没有证据表明现有药物对肺功能的长期下降具有显着影响，这是该病的标志。这种病。但是，COPD是国际准则中强调的内容。作为一种可治疗的疾病，目前控制稳定COPD的策略包括针对该疾病不同方面的几种个性化干预措施。这些干预措施大多是非药物性的，例如戒烟以防止肺功能加速丧失，流感和肺炎球菌疫苗以防止呼吸道感染，进行运动训练以提高运动耐力和呼吸困难，提供营养支持以防止体重减轻以及长期服用氧气可增加慢性呼吸衰竭患者的生存率。长效支气管扩张药的药物疗法可减轻症状和加重病情。重症COPD患者吸入皮质类固醇的摄入进一步降低了加​​重频率。

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