Comparison of hERG channel blocking effects of anti-arrhythmic mexiletine and its metabolite m-hydroxymexiletine (MHM)

Gualdani R.; Lentini G.; Moncelli M. R.

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Comparison of hERG channel blocking effects of anti-arrhythmic mexiletine and its metabolite m-hydroxymexiletine (MHM)

机译：抗心律失常美西律及其代谢物间羟基美西律（MHM）的hERG通道阻断作用比较

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来源
《The FEBS journal》 |2014年第1期|共1页
作者
Gualdani R.; Lentini G.; Moncelli M. R.;
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原文格式 PDF
正文语种 eng
中图分类生物化学;
关键词
cardiotoxicity; hERG channel;

机译：心脏毒性;hERG通道;

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1. Comparison of hERG channel blocking effects of anti-arrhythmic mexiletine and its metabolite m-hydroxymexiletine (MHM) [J] . Gualdani R., Lentini G., Moncelli M. R. The FEBS journal . 2014,第Suppla1期

机译：抗心律失常美西律及其代谢物间羟基美西律（MHM）的hERG通道阻断作用比较
2. Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action. [J] . Kiesecker C, Zitron E, Luck S, Naunyn-Schmiedeberg's Archives of Pharmacology . 2004,第6期

机译：Ia类抗心律不齐药物ajmaline阻断HERG钾通道：作用方式。
3. Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action [J] . Claudia Kiesecker, Edgar Zitron, Sonja Lück, Naunyn-Schmiedeberg's Archives of Pharmacology . 2004,第6期

机译：Ia类抗心律不齐药物ajmaline阻断HERG钾通道：作用方式
4. Synergistic anti-arrhythmic effects of combined blockade of sodium and ultra-rapid delayed rectifier potassium channels in human atria [C] . Haibo Ni, Dominic G. Whittaker, Wei Wang, Computing in Cardiology Conference . 2016

机译：钠和超快延迟整流钾通道联合阻断对人心房的协同抗心律失常作用
5. N-Glycosylation Modulates Gating and Antibiotic Block of the Human Potassium Channel, hERG1A [D] . Norring, Sarah A. 2010

机译：N糖基化调节人类钾通道hERG1A的门控和抗生素阻滞
6. Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine [O] . Roberta Gualdani, Francesco Tadini-Buoninsegni, Mariagrazia Roselli, 2015

机译：抗心律失常药美西律及其代谢物间羟基美西律对hERG钾通道的抑制作用
7. Comparison of Gating Properties and Use-Dependent Block of Na(v)1.5 and Na(v)1.7 Channels by Anti-Arrhythmics Mexiletine and Lidocaine [O] . Wang, Ying, Mi, Jianxun, Lu, Ka, 2015

机译：抗心律不齐美西律和利多卡因的门控性质和Na（v）1.5和Na（v）1.7通道的使用依赖区的比较

Comparison of hERG channel blocking effects of anti-arrhythmic mexiletine and its metabolite m-hydroxymexiletine (MHM)

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