Glutathione transferases in bacteria

Allocati N; Federici L; Masulli M; Di Ilio C

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Glutathione transferases in bacteria

机译：细菌中的谷胱甘肽转移酶

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Bacterial glutathione transferases (GSTs) are part of a superfamily of enzymes that play a key role in cellular detoxification. GSTs are widely distributed in prokaryotes and are grouped into several classes. Bacterial GSTs are implicated in a variety of distinct processes such as the biodegradation of xenobiotics, protection against chemical and oxidative stresses and antimicrobial drug resistance. In addition to their role in detoxification, bacterial GSTs are also involved in a variety of distinct metabolic processes such as the biotransformation of dichloromethane, the degradation of lignin and atrazine, and the reductive dechlorination of pentachlorophenol. This review article summarizes the current status of knowledge regarding the functional and structural properties of bacterial GSTs.

机译：细菌谷胱甘肽转移酶（GST）是酶超家族的一部分，该酶在细胞排毒中起关键作用。 GST广泛分布于原核生物中，并分为几类。细菌GST涉及多种不同的过程，例如异生物素的生物降解，针对化学和氧化应激的保护以及抗菌药物的耐药性。除了在排毒中的作用外，细菌GST还参与各种不同的代谢过程，例如二氯甲烷的生物转化，木质素和阿特拉津的降解以及五氯苯酚的还原性脱氯。这篇综述文章总结了有关细菌GST的功能和结构特性的知识的现状。

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《The FEBS journal》 |2009年第1期|共18页
作者
Allocati N; Federici L; Masulli M; Di Ilio C;
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正文语种 eng
中图分类生物化学;
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1. Glutathione-s-transferase activity and metabolism of glutathione conjugates by rhizosphere bacteria. [J] . R M Zablotowicz, R E Hoagland, M A Locke, Applied and Environmental Microbiology . 1995,第3期

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3. Estrogen receptor 1, Glutathione S-transferase P1, Glutathione S-transferase M1, and Glutathione S-transferase T1 Genes with Dysmenorrhea in Korean Female Adolescents [J] . Annals of laboratory medicine. . 2010,第1期

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4. Erectile Dysfunction Drugs and Protein Expression of Glutathione S-transferase and Glutathione Peroxidase in the Liver of Male Rats [C] . SALAH A. SHEWEITA, BASANT SALAMA, MOSTAFA HASSAN MOSTAFA International Conference on Energy Systems, Environment, Entrepreneurship and Innovation . 2015

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5. Computational modeling of the microsomal glutathione transferase-I-catalyzed reaction of glutathione with halogenated alkenes. [D] . Jolivette, Larry J. 2001

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6. Glutathione-S-Transferase Activity and Metabolism of Glutathione Conjugates by Rhizosphere Bacteria [O] . R. M. Zablotowicz, R. E. Hoagland, M. A. Locke, 1995

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7. Genetic polymorphisms of glutathione S-transferase Mu 1, glutathione S-transferase theta 1, and glutathione S-transferase P1 in oral squamous cell carcinoma: A case-control study in Iranian population [O] . Bahram Yaghmaei, Kaveh Yaghmaei, Mohammad Jafarian, 2015

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Glutathione transferases in bacteria

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