首页> 外文期刊>The Indian journal of medical research. >Mannose binding lectin (MBL) 2 gene polymorphism & its association with clinical manifestations in systemic lupus erythematosus (SLE) patients from western India
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Mannose binding lectin (MBL) 2 gene polymorphism & its association with clinical manifestations in systemic lupus erythematosus (SLE) patients from western India

机译:印度西部系统性红斑狼疮(SLE)患者的甘露糖结合凝集素(MBL)2基因多态性及其与临床表现的关系

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摘要

Background & objectives : Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease characterized by production of autoantibodies. Mannose binding lectin (MBL) is an important element of the innate defense system. t0 he present study was undertaken to determine whether variant alleles in MBL2 gene were associated with disease severity in SLE patients.
机译:背景与目的:系统性红斑狼疮(SLE)是一种典型的自身免疫性疾病,其特征在于自身抗体的产生。甘露糖结合凝集素(MBL)是先天防御系统的重要组成部分。本研究旨在确定MBL2基因的变异等位基因是否与SLE患者的疾病严重程度相关。

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