...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The British Journal of Nutrition >Effect of vitamin D, calcium and multiple micronutrient supplementation on vitamin D and bone status in Bangladeshi premenopausal garment factory workers with hypovitaminosis D: a double-blinded, randomised, placebo-controlled 1-year intervention.
【24h】

Effect of vitamin D, calcium and multiple micronutrient supplementation on vitamin D and bone status in Bangladeshi premenopausal garment factory workers with hypovitaminosis D: a double-blinded, randomised, placebo-controlled 1-year intervention.

机译：维生素D，钙和多种微量营养素的补充对孟加拉国绝经前维生素D缺乏症的服装工厂工人的维生素D和骨骼状况的影响：双盲，随机，安慰剂对照的1年干预。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Due to little outdoor activity and low dietary intake of vitamin D (VD), Bangladeshi low-income women are at risk for osteoporosis at an early age. The present study assessed the effect of VD, Ca and multiple micronutrient supplementation on VD and bone status in Bangladeshi young female garment factory workers. This placebo-controlled 1-year intervention randomly assigned 200 apparently healthy subjects (aged 16-36 years) to four groups: VD group, daily 10 mug VD; VD and Ca (VD-Ca) group, daily 10 mug VD+600 mg Ca; multiple micronutrient and Ca (MMN-Ca) group, 10 mug VD and other micronutrients + 600 mg Ca; a placebo group. Serum 25-hydroxyvitamin D (S-25OHD), intact parathyroid hormone (S-iPTH), Ca, phosphate and alkaline phosphatase were measured. Bone mineral density and bone mineral content were measured by dual-energy X-ray absorptiometry. All measurements were made at baseline and at 12 months. Significantly (P < 0.001) higher S-25OHD concentrations were observed in the supplemented groups than in the placebo group after the intervention. Supplementation had an effect (P < 0.001) on S-iPTH in the VD-Ca and MMN-Ca groups compared with the placebo group. Bone mineral augmentation increased at the femur in the supplemented groups. Supplementation with VD-Ca should be recommended as a strategic option to reduce the risk of osteomalacia and osteoporosis in these subjects. MMN-Ca may have analogous positive health implications with additional non-skeletal benefits
机译：由于很少的户外活动和饮食中维生素D（VD）的低摄入量，孟加拉国的低收入妇女在很小的时候就有患骨质疏松症的风险。本研究评估了孟加拉国年轻女性服装工厂工人的VD，Ca和多种微量营养素补充对VD和骨骼状况的影响。这项安慰剂对照的1年干预将200名明显健康的受试者（年龄16-36岁）随机分为四组：VD组，每天10杯VD; VD和Ca（VD-Ca）组，每日10杯VD + 600 mg Ca;多种微量营养素和Ca（MMN-Ca）组，10杯VD和其他微量营养素+ 600 mg Ca;安慰剂组。测量血清25-羟基维生素D（S-25OHD），完整的甲状旁腺激素（S-iPTH），钙，磷酸和碱性磷酸酶。骨矿物质密度和骨矿物质含量通过双能X射线吸收法测量。所有测量均在基线和12个月时进行。干预后，补充组的S-25OHD浓度明显高于安慰剂组（P <0.001）。与安慰剂组相比，VD-Ca和MMN-Ca组的补充品对S-iPTH有影响（P <0.001）。在补充组中，股骨的骨矿物质增加增加。应建议补充VD-Ca作为减少这些受试者骨软化症和骨质疏松症风险的战略选择。 MMN-Ca可能具有类似的积极健康影响，并具有额外的非骨骼益处

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号