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首页> 外文期刊>The British Journal of Nutrition >Maternal low-protein diet-induced delayed reflex ontogeny is attenuated by moderate physical training during gestation in rats.
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Maternal low-protein diet-induced delayed reflex ontogeny is attenuated by moderate physical training during gestation in rats.

机译:在妊娠期间,通过适度的体育锻炼可以降低母体低蛋白饮食诱导的延迟反射个体发育。

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摘要

We evaluated the effects of moderate- to low-intensity physical training during gestation on reflex ontogeny in neonate rats whose mothers were undernourished. Virgin female Wistar rats were divided into four groups as follows: untrained (NT, n 7); trained (T, n 7); untrained with a low-protein diet (NT+LP, n 7); trained with a low-protein diet (T+LP, n 4). Trained rats were subjected to a protocol of moderate physical training on a treadmill over a period of 4 weeks (5 d/week and 60 min/d, at 65 % of VO2max). After confirming the pregnancy, the intensity and duration of the exercise were reduced. Low-protein groups were provided with an 8 % casein diet, and controls were provided with a 17 % casein diet. Their respective offspring were evaluated (during the 10th-17th days of postnatal life) in terms of physical feature maturation, somatic growth and reflex ontogeny. Pups born to mothers provided with the low-protein diet during gestation and lactation showed delayed physical feature and reflex maturation and a deficit in somatic growth when compared with controls. However, most of these deficiencies were attenuated in pups of undernourished mothers undergoing training. In conclusion, physical training during gestation attenuates the effects of perinatal undernutrition on some patterns of maturation in the central nervous system during development.
机译:我们评估了孕期中低强度体育锻炼对母亲营养不良的新生大鼠反射个体发育的影响。原始雌性Wistar大鼠分为以下四组:未经训练(NT,n 7);未受过训练的大鼠(n = 7)。训练有素(T,n 7);未经过低蛋白饮食训练(NT + LP,n 7);接受低蛋白饮食训练(T + LP,n 4)。训练有素的大鼠在跑步机上接受了为期4周(5 d /周和60 min / d,VO2max为65%)的中度体育锻炼的规程。确认怀孕后,运动强度和持续时间减少。低蛋白组的酪蛋白饮食量为8%,对照组的酪蛋白饮食量为17%。在生理特征成熟,体细胞生长和反射个体发育方面,对他们各自的后代进行了评估(在出生后的第10-17天)。与对照组相比,在妊娠和哺乳期间提供低蛋白饮食的母亲所生的幼仔表现出延迟的身体特征和反射性成熟以及体细胞生长不足。但是,这些营养不足的大多数在正在接受培训的营养不良母亲的幼崽中得到了缓解。总之,妊娠期间的体育锻炼可减轻围产期营养不良对发育过程中中枢神经系统某些成熟模式的影响。

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