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首页> 外文期刊>The British Journal of Nutrition >Worldwide burden of gastric cancer in 2012 that could have been prevented by increasing fruit and vegetable intake and predictions for 2025
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Worldwide burden of gastric cancer in 2012 that could have been prevented by increasing fruit and vegetable intake and predictions for 2025

机译：2012年全球胃癌负担可以通过增加水果和蔬菜的摄入量以及对2025年的预测来预防

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摘要

The regional and temporal variation in patterns of fruit and vegetable intake contributes to differences in the impact on gastric cancer burden across regions and over the years. We aimed to estimate the proportion and absolute number of gastric cancer cases that could have been prevented in 2012 with an increase in fruit and vegetable intake up to the levels defined by the Global Burden of Disease as the theoretical minimum-risk exposure distribution (300 and 400 g/d, respectively), as well as the corresponding figures expected for 2025. Preventable fractions (PF) were computed for 161 countries, using data on fruit and vegetable availability in 1997 and 2010 and published estimates of the magnitude of the association between fruit and vegetable intake and gastric cancer, assuming a time lag of approximately 15 years. Countries classified as very high Human Development Index (HDI) presented median PF in 2012 much lower than low-HDI countries for both fruits (3.0 v. 10.2%, P0.001) and vegetables (6.0 v. 11.9%, P0.001). For vegetables only, PF significantly decreased until 2025 in most settings; however, this corresponded to a reduction in the absolute number of preventable gastric cancer cases in less than half of the countries. Increasing fruit and vegetable intake would allow preventing a relatively high proportion of gastric cancer cases, mostly in developing countries. Although declines in PF are predicted in the near future, changes in order to achieve healthier lifestyles may be insufficient to overcome the load of demographic variation to further reduce the gastric cancer burden.
机译：水果和蔬菜摄入方式的区域和时间变化导致跨地区和多年来对胃癌负担的影响差异。我们的目标是估计在2012年可以预防的胃癌病例的比例和绝对数量，因为水果和蔬菜的摄入量增加到全球疾病负担定义为理论最低风险暴露水平的水平（300和分别为400克/天）和2025年的预期相应数字。使用1997年和2010年水果和蔬菜供应量的数据，并发布了对假设水果和蔬菜的摄入量以及胃癌的时滞约为15年。被归类为人类发展指数（HDI）很高的国家，水果（3.0 vs. 10.2％，P <0.001）和蔬菜（6.0 vs. 11.9％，P <0.001）的PF中值均大大低于低HDI国家。 。在大多数情况下，仅对于蔬菜而言，PF会显着下降，直到2025年。然而，这对应于少于一半国家中可预防的胃癌病例绝对数量的减少。水果和蔬菜摄入量的增加将可以预防相对较高比例的胃癌病例，大部分发生在发展中国家。尽管预计在不久的将来PF会下降，但是为了实现更健康的生活方式而进行的改变可能不足以克服人口变化的负担，从而进一步减轻胃癌的负担。

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