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首页> 外文期刊>The Canadian journal of hospital pharmacy. >Should All High-Risk Patients Receive Acetylsalicylic Acid 81 mg Daily for Primary Prevention of Cardiovascular Disease?
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Should All High-Risk Patients Receive Acetylsalicylic Acid 81 mg Daily for Primary Prevention of Cardiovascular Disease?

机译：所有高危患者是否应每天接受81毫克乙酰水杨酸用于心血管疾病的一级预防？

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摘要

A cornerstone for the discussion of using acetylsalicylic acid (ASA) for primary prevention of cardiovascular disease is determining which patients are at high risk and then determining if low-dose ASA would reduce that risk. Stratification of cardiovascular disease risk is a strategy employed by many health care providers to determine if individual patients are at risk of experiencing a cardiovascular event, given known risk factors such as age, smoking, hypertension, dyslipidemia, and diabetes mellitus. Many risk stratification tools are available, the most commonly used in Canada being the Framingham cardiovascular disease risk estimation tool. This tool (www.framinghamheartstudy. org/risk/index.html), as well as many other risk calculators for various cardiovascular outcomes of interest, was developed by the Framingham Heart Study investigators. A high-risk population is generally defined as having a 10-year risk of cardiovascular disease of 20% or greater, with myocardial infarction being the most prevalent event within the spectrum of cardiovascular disease that would lead to high-risk status.
机译：使用乙酰水杨酸（ASA）进行心血管疾病一级预防的讨论的基础是确定哪些患者处于高风险中，然后确定低剂量ASA是否可以降低该风险。在已知的风险因素（例如年龄，吸烟，高血压，血脂异常和糖尿病）下，心血管疾病风险的分层是许多医疗服务提供商采用的策略，用于确定个体患者是否有发生心血管事件的风险。有许多风险分层工具可用，在加拿大最常用的是弗雷明汉心血管疾病风险估计工具。该工具（www.framinghamheartstudy。org / risk / index.html）以及许多其他有趣的计算器，可用于关注各种心血管结果，由Framingham心脏研究的研究人员开发。高风险人群通常被定义为10年心血管疾病风险为20％或更高，其中心肌梗塞是导致高风险状态的心血管疾病范围内最普遍的事件。

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