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首页> 外文期刊>The Canadian journal of clinical pharmacology =: Journal canadien de pharmacologie clinique >Estimating the neurocognitive effects of an early intervention program for children with prenatal alcohol exposure
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Estimating the neurocognitive effects of an early intervention program for children with prenatal alcohol exposure

机译：评估早期干预方案对产前酒精暴露儿童的神经认知作用

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Background: Animal studies suggest that early intervention in pups exposed heavily to ethanol in utero can mitigate their neurocognitive damage. No human studies on this promising mechanism exists. Methods: Breaking the Cycle is an early intervention program for drug-and alcohol addicted mothers and their young children. We compared BSID-III scores between infants heavily exposed to ethanol and a group exposed only to drugs of abuse, mainly cocaine. Both groups benefited from all aspects of our early intervention program. Results: The two groups did not differ in any aspect of the BSID-III. These data are in contradistinction to the damage seen in heavily ethanol- exposed infants not benefiting from early intervention. Conclusions: This pilot suggests that early intervention may mitigate some of the well described damages caused by heavy in utero alcohol exposure.
机译：背景：动物研究表明，对子宫内大量暴露于乙醇的幼仔进行早期干预可以减轻它们的神经认知损害​​。尚无人对这种有前途的机制进行研究。方法：打破周期是一项针对吸毒和酗酒的母亲及其幼儿的早期干预计划。我们比较了严重接触乙醇的婴儿和仅接触滥用药物（主要是可卡因）的婴儿之间的BSID-III评分。两组都受益于我们早期干预计划的各个方面。结果：两组在BSID-III的任何方面均没有差异。这些数据与大量乙醇暴露的婴儿没有从早期干预中受益的损害相矛盾。结论：该试验表明早期干预可减轻因大量暴露于子宫内酒精引起的一些已充分描述的损害。

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