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首页> 外文期刊>The Canadian journal of hospital pharmacy. >Prospective Audit and Feedback of Antimicrobial Stewardship in Critical Care: Program Implementation, Experience, and Challenges
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Prospective Audit and Feedback of Antimicrobial Stewardship in Critical Care: Program Implementation, Experience, and Challenges

机译：重症监护中抗菌药物管理的前瞻性审计和反馈：计划实施，经验和挑战

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Antimicrobial stewardship has been defined as the limitation of inappropriate use of antimicrobials while optimizing the selection, dosing, route, and duration of antimicrobial therapy to maximize clinical cure or prevent infection; limiting unintended consequences, such as emergence of resistance, occurrence of adverse drug events, and selection of pathogenic organisms (such as Clostridium difficile); and minimizing cost.' Because of increased resistance to antimicrobial agents and a lack of novel agents, there has been increasing pressure for judicious use of currently available antimicrobials, to ensure that their activity is preserved.2 In Canada, the need for antimicrobial stewardship has been recognized as a patient safety issue by the Institute for Safe Medication Practices Canada, the Ontario Agency for Health Protection and Promotion, and the Ontario Ministry of Health and Long-Term Care, and together these agencies have launched the Ontario Antimicrobial Stewardship Project.3 Accreditation Canada has also proposed that it be a Required Organizational Practice for institutions to have a program to appropriately manage antimicrobial resources.4 However, despite the well-recognized need to institute antimicrobial stewardship programs, detailed descriptions of the steps taken and challenges encountered in implementing successful programs are lacking in the literature. The purpose of this article is to describe our experience with the development of an antimicrobial stewardship program at a university-affiliated teaching hospital.
机译：抗菌管理已被定义为在优化抗菌治疗的选择，剂量，途径和持续时间以最大程度地临床治愈或预防感染的同时不适当使用抗菌剂的局限性;限制意想不到的后果，例如耐药性的出现，药物不良事件的发生以及病原生物的选择（例如艰难梭菌）;并降低成本。”由于对抗菌剂的抗药性增强，并且缺乏新型药物，因此，明智地使用目前可用的抗菌剂以确保其活性得以维持的压力越来越大。2在加拿大，人们已经认识到需要进行抗菌素管理工作加拿大安全用药实践研究所，安大略省健康保护和促进局以及安大略省卫生和长期护理部的安全问题，以及这些机构共同发起了安大略省抗菌素管理项目。3加拿大的认证也已提出4虽已广为人知，需要制定抗菌素管理计划，但对于成功实施抗菌素管理计划所采取的步骤和所遇到的挑战，尚缺乏详尽的说明。文献。本文的目的是描述我们在大学附属教学医院开发抗菌素管理计划的经验。

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